The GemCode Technology

A fully integrated solution
for RNA and DNA analysis

The Chromium System is powered by 10x GemCode Technology

Our proprietary 10x GemCode Technology fuels our Chromium System with an innovative reagent delivery system, set of algorithms and turn-key software analysis tools that enable the discovery of previously inaccessible genetic information at massive rate and scale.

Our GemCode Technology creates a unique reagent delivery system that partitions cells or arbitrarily long DNA molecules (including >100 kb) and prepares sequencing libraries in parallel such that all fragments produced within a partition share a common barcode.

A simple workflow combines large partition numbers with a massively diverse barcode library to generate >100,000 barcode containing partitions in a matter of minutes.

Solid phase reagent delivery
Fluid partitioning
Liquid phase biochemistry

The Chromium Software Suite maps short-read data to original long molecules using the barcodes provided by our GemCode Technology.

Algorithms utilize this information to recover long range information, enabling applications impossible with short read sequencing, including haplotype phasing and vastly improved structural variant detection.

Easily Integrated Into Existing Lab Infrastructure

Our GemCode Technology leverages existing short-read sequencers and is easily integrated into existing laboratory workflows.

10x Reagent
~1 ng DNA
10x GemCode
Barcoding &
Library Construction
Sequence genome
10x Long Ranger
10x Loupe
Report & Visualization