10x’s products enable a diverse set of sequencing applications, bringing unprecedented levels of depth to genomic analysis.
The GemCode™ Technology has been adopted for use in multiple applications, including whole-genome phasing and structural variant analysis, de novo genome assembly, remapping of difficult regions of the genome, and dynamic gene expression of single cells.Application Notes | DNA Application Gallery | Single Cell Application Gallery
DNA Application Gallery
Resolve Compound Heterozygosity
Establish cis or trans relationships between variants without trio sequencing.
Detect Structural Variants
Detect multiple classes of structural variants, including gene fusions, duplications, deletions and translocations.
Resolve the Genome Into Multi-Megabase Phase Blocks
Phase the full spectrum of variants (SNVs, indels, and large-scale structural rearrangements) into ultra long multi-megabase phase blocks, enabling a full understanding of diploid genome sequence.
Uncover Previously Inaccessible Parts of the Genome
Using the Lariat™ Linked-Read Aligner, map reads that cannot normally be mapped, enabling variant calling and phasing in regions normally inaccessible to short reads.
Multi-Megabase Diploid De Novo Assembly
Using the Supernova™ Assembler, reconstruct multi-megabase diploid assemblies, preserving phasing information for small variants, structural rearrangements and novel sequence without the need for a reference.
Single Cell Application Gallery
Interrogate Heterogeneous Cell Populations
Profiling 1,000s to 10,000s of cells per experiment increases sensitivity and accuracy for the detection of rare cell types.
Differential Expression Identifies Cell Cycle Phase
Understand dynamic processes by interrogating gene expression on a cell-by-cell level.