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Scientist II/ Senior Scientist – Chemistry

Location: Pleasanton, CA


Location: Pleasanton, CA

10x Genomics is building tools for scientific discovery that reveal and address the true complexities of biology and disease. Through a combination of novel microfluidics, chemistry and bioinformatics, our award-winning Chromium™ System is enabling researchers around the world to more fully understand the fundamentals of biology at unprecedented resolution and scale. Learn more at


Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. There’s a dynamic energy here, and we’re looking for the best of the best to be a part of it. We are seeking talented professionals excited to build new technology that advances scientific research while growing their career within a dynamic, supportive environment.

We are seeking an outstanding Scientist to join our 10x Genomics team to drive research and next-generation product development at our Pleasanton Headquarters.

This is a unique cross-disciplinary chemistry position that will require working closely with a variety of other disciplines including: Molecular Biology, Microfluidics, Computational Biology and Consumable Process Development. The ideal candidate will have a chemistry background with a broad working knowledge of biomaterials, nanotechnology, tissue culture, bioconjugation and analytical chemistry and the capability of applying this know-how creatively/independently within a fast-paced work environment. Individuals applying for this position must be highly motivated self-starters, action driven, collaborative, have exceptional attention to detail, be flexible in shifting focus between a variety of projects as required, communicate effectively, and provide immediate contribution.

Job level and title will be commensurate with experience.

Key Responsibilities

  • Collaborate across multiple disciplines to identify, develop and implement novel chemistry solutions and translate these solutions from R&D to elegant and robust commercial product lines  
  • Undertake paper studies and basic exploration of new scientific or product concepts to determine their feasibility
  • Establish analytical assays for product and component characterization
  • Contribute to design decisions through effective communication of experimental design, results, and, conclusions at regular data-driven product development meetings
  • Productive execution of well thought out experiments, accurate recording of results along with in-depth analysis and reporting of these results
  • Integrate custom chemistries into new and/or existing workflows

Required Skills and Background

  • PhD in Chemical Engineering, Chemistry or Bioengineering with 3-8 years postgraduate experience in academia or industry.
  • 5+ years relevant experience in bioconjugation, biomaterials, polymer chemistry, analytical chemistry and tissue culture for life science products and applications
  • Strong ability to perform multidisciplinary research and ability to integrate a broad range of scientific and engineering disciplines
  • Hands-on experience with a broad range of bioconjugation and surface modification chemistries; and subsequent characterization via analytical and biological assays including; UV-Vis, HPLC, GPC, DLS, flow cytometry and/or bioimaging
  • Experience in standard molecular biology techniques such as sample preparation, nucleic acid amplification, qPCR, gel electrophoresis etc.
  • Hands-on experience in cell culture and cell staining, microscopy and related biological/in vitro cell-based assays
  • Exceptionally strong collaboration and communication skills
  • Desire to be part of a rapidly evolving, fast-paced organization, with a compelling technology, and taking products and processes to the next level


Desired Skills and Background

  • Understanding and experience with next-generation sequencing workflows and data analysis
  • Experience with delivery systems like hydrogels, micro and nanoparticles
  • Demonstrated ability to create and implement complex multi-step assay schemes.
  • Ability to perform under pressure and adapt to changes (e.g., priorities and timelines)
  • Experience with microscopy, high-speed imaging, and/or quantitative fluorescence imaging

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.


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Pleasanton, CA

10x Genomics
6230 Stoneridge Mall Road
Pleasanton, CA 94588-3260
+1 925 401 7300
+1 800 709 1208

San Francisco, CA

10x Genomics
160 Spear St.,
Suite 1130
San Francisco, CA 94105
+1 925 401 7300
+1 800 709 1208

Leiden, The Netherlands

10x Genomics B.V.
Crown Business Center Key Point II,
Schipholweg 103,
2316 XC Leiden,
The Netherlands

Stockholm, Sweden

Spatial Transcriptomics,
Part of 10x Genomics, Inc
Södra Fiskartorpsvägen 15C,
114 33 Stockholm,


10x Genomics Pte Ltd
Science Park 2,
20 Science Park Road,
#02-32A/33 Teletech Park,
Singapore 117674

Shanghai, China

10x Genomics (Shanghai) Co., Ltd
2421, Cloud 9 International Plaza,
No 1018 Changning Road,
Shanghai, 200042 China