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Senior Computational Biologist – Stockholm, Sweden

Location: Stockholm, Sweden

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It’s a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they didn’t even know they could ask. Our tools have enabled fundamental discoveries described in over 800 peer-reviewed publications across multiple application areas, including cancer, immunology, and neuroscience.  

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. The innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. 

Computational Biologist: Product Development

Location: Stockholm, Sweden

We are looking for an outstanding individual to join our Computational Biology group. You will work closely with talented biochemists, microfluidics engineers, chemists and software engineers to develop single-cell and spatial genomic assays. Our products have allowed researchers to study biology at unprecedented resolution yielding insights in diverse fields such as cancer biology, immunology, neuroscience, developmental and basic biology.

 

You will develop computational methods and analyses to measure and improve product performance during a fast-paced product development cycle. This includes discovering issues through careful analysis of sequencing data and working collaboratively with the interdisciplinary product team to help resolve them. You will also develop metrics and other automated analyses that will eventually be used by customers to benchmark assay performance.

 

You have a strong background in statistics, data analysis and you are deeply knowledgeable about existing genomic assays and the subtleties of NGS data. You are a good programmer who can take an idea and quickly implement it in code. You are able to communicate your ideas and work effectively with an interdisciplinary team and incorporate their feedback into your analysis. You are a strategic thinker, highly motivated, action driven and flexible in changing direction and methods. You thrive in a fast paced environment, excel at managing multiple priorities, communicate clearly and get the job done.

 

Key Responsibilities

  • Establish prototype NGS processing pipelines for novel genomic assays
  • Develop analysis tool to measure and guide development of genomic assays
  • Use exploratory analysis and statistical models to troubleshoot and optimize the assay
  • Build statistical analyses into robust tools for monitoring performance over time
  • Define experimental metrics for measuring assay quality, and determine goals & priorities for assay development work.
  • Design proof-of-concept experiments, analyze and interpret the data to demonstrate the unique power of the 10x Genomics platform internally and externally

 

Required Skills and Background

  • PhD or MS plus equivalent experience in a quantitative field (e.g. physics, mathematics, computer science, electrical engineering, computational/systems biology or related field)
  • Ability to quickly conceive and implement custom statistical methods and algorithms and apply them to large data sets
  • Ability to work in a fast-paced and quickly changing environment
  • Ability to communicate complex ideas with an interdisciplinary team
  • Has experience with the analysis of NGS data
  • Ability to work independently

Desired Skills and Background  

  • Strong programming ability in Python or R
  • A deep intuition for the processes utilized by current NGS technologies
  • Creative problem solver who obsesses over finding useful information in data
  • Hands on experience with NGS data tools (e.g. bwa, samtools, GATK)
  • Experience analyzing multiplexed imaging datasets (e.g. in situ sequencing, multiplexed FISH)
  • A combination of mathematical depth with a healthy respect for the imperfections inherent in real-world data
  • Strong interest in applying analytical tools to solve important and interesting biological problems

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.

 

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Pleasanton, CA

10x Genomics
6230 Stoneridge Mall Road
Pleasanton, CA 94588-3260
+1 925 401 7300
+1 800 709 1208

San Francisco, CA

10x Genomics
Three Embarcadero Center,
Ste. 2330
San Francisco, CA 94111
+1 925 401 7300
+1 800 709 1208

Leiden, The Netherlands

10x Genomics B.V.
Crown Business Center Key Point II,
Schipholweg 103,
2316 XC Leiden,
The Netherlands

Stockholm, Sweden

Spatial Transcriptomics,
Part of 10x Genomics, Inc
Södra Fiskartorpsvägen 15C,
114 33 Stockholm,
Sweden

Singapore

10x Genomics Pte Ltd
Science Park 2,
20 Science Park Road,
#02-32A/33 Teletech Park,
Singapore 117674

Shanghai, China

10x Genomics (Shanghai) Co., Ltd
2421, Cloud 9 International Plaza,
No 1018 Changning Road,
Shanghai, 200042 China