Join Our Team

Senior Manufacturing Engineer

Location: Pleasanton, CA

10x Genomics is building tools for scientific discovery that reveal and address the true complexities of biology and disease. Through a combination of novel microfluidics, chemistry and bioinformatics, our award-winning Chromium™ System is enabling researchers around the world to more fully understand the fundamentals of biology at unprecedented resolution and scale. Learn more at


Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. There’s a dynamic energy here, and we’re looking for the best of the best to be a part of it. We are seeking talented professionals excited to build new technology that advances scientific research while growing their career within a dynamic, supportive environment.

Senior Manufacturing Engineer

10x Genomics is a rapidly growing company in the life sciences, whose core technology combines advances in instrumentation, chemistry, biochemistry, microfluidics and computational biology.

10x is looking for an outstanding individual to join its instrument development and sustaining team. This person will be responsible for manufacturing support for complex system equipment.

The ideal candidate will have a strong background in engineering and systems troubleshooting.  Knowledge and hands on experience with contract manufacturing, production assembly, calibration and control for instrument manufacturing and previous experience in managing manufacturing with contract vendors are required.


Key Responsibilities

  • Work to assure continuing quality of 10x hardware products
  • Drive the NPI activities to launch new products
  • Engage with contract manufactures to drive root cause investigations, implement corrective actions, monitor and trend RMA actions, and provide for continuous manufacturing process improvements
  • Interfaces with design engineering and Product Management to coordinate the release of new products and firmware
  • Work with design engineering to correct issues found during manufacturing of new products
  • Provide in-house failure analysis and repair of complex biotech equipment
  • Conduct regression testing of new firmware candidate builds and provide feedback to developers on bugs
  • Design and development of manufacturing test fixtures as required. Design fixtures and tooling to help reduce cost of machine setup and reduce scrap
  • Define, measure and report key metrics for production quality and cost


Required Skills and Qualifications

  • Bachelor’s degree in Engineering: Mechanical, Electrical or Manufacturing with 7+ years of experience, or MS/ PhD with 5-7 years of experience.
  • Work history with several successful iterations of Design to Manufacturing transfers
  • Ability to review and update mechanical drawings, ability to read schematics
  • Creation of FMEAs, ECOs and work instructions
  • Experienced in Supplier Engagement and support, domestic and off shore
  • Working knowledge of manufacturing and assembly techniques, machining, injection molding, instrument and consumables for biotech
  • Experience working with instrument manufacturing under ISO 9001 or ISO 13485 standards
  • Experience with SolidWorks, JMP or programming languages a plus
  • Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level.

 All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.


Apply now Back to Careers

Pleasanton, CA

10x Genomics
7068 Koll Center Parkway,
Suite 401
Pleasanton, CA 94566
+1 925 401 7300
+1 800 709 1208

San Francisco, CA

10x Genomics
160 Spear St.,
Suite 1130
San Francisco, CA 94105
+1 925 401 7300
+1 800 709 1208

Leiden, The Netherlands

10x Genomics B.V.
Crown Business Center Key Point II,
Schipholweg 103,
2316 XC Leiden,
The Netherlands
+31 (20) 888 6622

Stockholm, Sweden

Spatial Transcriptomics,
Part of 10x Genomics, Inc
Södra Fiskartorpsvägen 15C,
114 33 Stockholm,


10x Genomics Pte Ltd
Science Park 2,
20 Science Park Road,
#02-32A/33 Teletech Park,
Singapore 117674

Shanghai, China

10x Genomics (Shanghai) Co., Ltd
2421, Cloud 9 International Plaza,
No 1018 Changning Road,
Shanghai, 200042 China

Order your 10x system, today.