Join Our Team

Senior Opto-Mechanical Engineer

Location: Pleasanton, CA

 10x Genomics is building tools for scientific discovery that reveal and address the true complexities of biology and disease. Through a combination of novel microfluidics, chemistry and bioinformatics, our award-winning Chromium™ System is enabling researchers around the world to more fully understand the fundamentals of biology at unprecedented resolution and scale. Learn more at


Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. There’s a dynamic energy here, and we’re looking for the best of the best to be a part of it. We are seeking talented professionals excited to build new technology that advances scientific research while growing their career within a dynamic, supportive environment.

Senior Opto-Mechanical Engineer

10x is seeking an outstanding individual to join its growing Engineering and Product Development team in developing new technologies, devices, and instrumentation for breakthrough next-generation sequencing (NGS) applications. These instruments may consist of a combination of optical excitation and detection components, actuators, electronics, fluidics components, and temperature controllers to process various types of biological samples in new ways!


Key Responsibilities

  • Responsible for the design, development, and release of opto-mechanical systems & subsystems
  • Work with scientists, engineers, manufacturing and others to translate concepts and requirements through development and into production-ready, robust designs
  • Design, build, test, and troubleshoot breadboards, prototypes, and production designs
  • Select and work with vendors to build and purchase components
  • Document designs and processes (Design Requirements, Design Reviews, Drawings, Analysis, Testing, ECOs)
  • Ensure conformance with company development process and standards
  • Work with process and manufacturing engineers to ensure high quality production of products

Required Skills and Background

  • Bachelor's degree or higher in Mechanical Engineering, Physics, Optics, or related discipline
  • Minimum of 8 years relevant industry experience
  • Demonstrated expertise in opto-mechanical and precision mechanism design
  • Solid understanding of basic optics and optical components
  • Proficient in SolidWorks or Creo
  • Understanding of GD&T and statistical tolerance analysis
  • Experience taking a concept from prototype to production
  • Experience preparing reports and design reviews for cross functional groups

Desired Skills and Background

  • Experience with optical instrumentation in biotechnology or medical devices
  • Experience in a multi-disciplinary team including chemistry or biology
  • Excellent written and verbal communication skills in English
  • High energy and interest in working in a growing startup environment
  • Hands-on, can-do approach
  • Knowledge of software programming or electrical engineering design

For more information, please contact

or submit your resume at


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Pleasanton, CA

10x Genomics
7068 Koll Center Parkway,
Suite 401
Pleasanton, CA 94566
+1 925 401 7300
+1 800 709 1208

San Francisco, CA

10x Genomics
160 Spear St.,
Suite 1130
San Francisco, CA 94105
+1 925 401 7300
+1 800 709 1208

Leiden, The Netherlands

10x Genomics B.V.
Crown Business Center Key Point II,
Schipholweg 103,
2316 XC Leiden,
The Netherlands
+31 (20) 888 6622

Stockholm, Sweden

Spatial Transcriptomics,
Part of 10x Genomics, Inc
Södra Fiskartorpsvägen 15C,
114 33 Stockholm,


10x Genomics Pte Ltd
Science Park 2,
20 Science Park Road,
#02-32A/33 Teletech Park,
Singapore 117674

Shanghai, China

10x Genomics (Shanghai) Co., Ltd
2421, Cloud 9 International Plaza,
No 1018 Changning Road,
Shanghai, 200042 China

Order your 10x system, today.