Senior Scientist – Assay Development
Location: Pleasanton, California
At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It’s a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.
We enable scientists to advance their research, allowing them to address scientific questions they didn’t even know they could ask. Our tools have enabled fundamental discoveries described in over 800 peer-reviewed publications across multiple application areas, including cancer, immunology, and neuroscience.
Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. The innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.
Scientist/Senior Scientist – Molecular Biology
We are looking for an exceptional scientist to drive new research and product development efforts in our Molecular Biology department.
The ideal candidate will have a solid knowledge in nucleic acid-modifying assays and/or proteomic assays, a proven track-record of developing innovative biochemistry/molecular biology protocols for detecting analytes (nucleic acids, proteins, metabolites, etc.) in tissues, as well as broad microscopy experience.
He/she should be driven by building innovative, robust and truly enabling products and enjoy working in a truly multi-disciplinary environment. The successful candidate in this position will interact closely with colleagues in computational biology, software, chemistry, and microfluidics.
- Conceive and develop novel biochemistry/molecular biology assay schemes for applications including spatial transcriptomics, highly-multiplexed imaging, molecular probing and tissues chemistry/biochemistry.
- Plan and perform systematic workflow and reagent optimization by modeling, identification of critical factors, and use of formal design of experiment (DOE) approaches
- Contribute biochemistry/molecular biology/pathology expertise and leadership to cross-disciplinary product development teams
- Work closely with computational biologists to interpret data generated by novel and optimized assay schemes
- Work closely with process development staff to develop quality control and manufacturing strategies for novel or optimized reagents
Required Skills and Background
- MD or MD/PHD with a minimum of 5 years post-graduate experience in academia and/or industry. PhD in chemistry, biochemistry, pathology, molecular biology, or a related field with a minimum of 3 years post-graduate experience in academia and/or industry .
- Proven ability to design novel biochemistry/molecular biology assay schemes, as evidenced by peer-reviewed publications, published patents, or commercialized products
- Familiarity with tissue-staining principles
- Familiarity with data analysis
- Strong organizational skills
- Strong written and oral communication skills
- Strong troubleshooting and problem solving skills
- Ability to work in a fast-paced and quickly changing environment
- Desire to build game-changing technologies and impact the world of life science research
Desired Skills and Background
- Spatial transcriptomics, highly-multiplexed imaging or pathology
- Experience with FFPE-tissue processing methods is a plus
- Experience in microscopy and broad image-analysis
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.