Join Our Team

Senior Mechanical Design Engineer

Location: Pleasanton, CA

10x Genomics is building tools for scientific discovery that reveal and address the true complexities of biology and disease. Through a combination of novel microfluidics, chemistry and bioinformatics, our award-winning Chromium™ System is enabling researchers around the world to more fully understand the fundamentals of biology at unprecedented resolution and scale. Learn more at


Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. There’s a dynamic energy here, and we’re looking for the best of the best to be a part of it. We are seeking talented professionals excited to build new technology that advances scientific research while growing their career within a dynamic, supportive environment.


Senior Mechanical Design Engineer

 10x Genomics is looking for an outstanding individual to join its Manufacturing Systems Engineering team supporting our ultra-precision mechanical designs and execution of 10x Genomics products.  The ideal candidate will have a strong background in Mechanical Engineering of ultra-precision designs with +/-0.5um tolerances.   Demonstrated hands on experience with Solid Works and CAM software with demanding precision is required.  Previous experience in producing mechanical designs that are manufacturing to ultra-precision with in house milling systems is required.


Key Responsibilities

  • Responsible for the design, development, and release of ultra-precision mechanical designs
  • Translation of SolidWorks designs using CAM into g-code for in-house milling
  • Engage with internal machinist, drive milling of designs and incorporate feedback from metrology data to root cause investigations, implement corrective actions, monitor and implement continuous machining process improvements
  • Interface with R&D microfluidics team to transfer designs and to coordinate the release of new products
  • Work with metrology engineers, microfluidics, machinist and injection molding vendors, to correct issues found during manufacturing of new products
  • Design and development of manufacturing test fixtures as required. Design fixtures and tooling to help reduce cost of machine setup and reduce scrap.
  • Support manufacturing automation with Mechanical design and design reviews as needed


Required Skills and Qualifications

  • Bachelor’s degree in Mechanical Engineering with 7+ years of experience in ultra-precision mechanical design.
  • Proficient in SolidWorks
  • Understanding of GD&T and statistical tolerance analysis
  • Work history with several successful iterations of ultra-precision designs tranfererred successfully to manufacturing
  • Experienced in Supplier Engagement and support, domestic and off shore
  • Working knowledge of manufacturing techniques, machining, injection molding and consumables for biotech
  • Experience working with under ISO 9001
  • Experience with JMP, Minitab or programming languages a plus
  • Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level.

 All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.




Apply now Back to Careers

加利福尼亚州 普莱森顿

10x Genomics
7068 Koll Center Parkway,
Suite 401
Pleasanton, CA 94566
+1 925 401 7300
+1 800 709 1208

加利福尼亚州 旧金山

10x Genomics
160 Spear St.,
Suite 1130
San Francisco, CA 94105
+1 925 401 7300
+1 800 709 1208

荷兰 莱顿

10x Genomics B.V.
Crown Business Center Key Point II,
Schipholweg 103,
2316 XC Leiden,
The Netherlands
+31 (20) 888 6622

瑞典 斯德哥尔摩

Spatial Transcriptomics,
Part of 10x Genomics, Inc
Södra Fiskartorpsvägen 15C,
114 33 Stockholm,


10x Genomics Pte Ltd
Science Park 2,
20 Science Park Road,
#02-32A/33 Teletech Park,
Singapore 117674

中国 上海

10x Genomics(上海)有限公司