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AAI 2018 – American Association for Immunology
May 4 - May 8
10X GENOMICS WORKSHOP
New Solutions for Single Cell Immune Profiling
High-throughput single-cell genomics has transformed our understanding of complex cell populations. Oligonucleotide-labeled antibodies allow integration of cellular protein and transcriptome measurements at a single-cell level, with the number of protein markers assayed simultaneously far surpassing what can be measured by cytometry-based approaches. CITE-seq is compatible with existing single-cell sequencing approaches and will readily scale as the throughput of scRNA-seq methods increases. We present an in-depth characterization of T cell populations in the human immune system using a panel of ~80 antibodies revealing complexity not previously observed by scRNA-seq alone.
Monday, May 7
12:30 – 1:15pm
Workshop Room #2
- Chair, Introduction and Updates from 10x Genomics: Brian Fritz, PhD, Strategic Marketing, 10x Genomics
- Highly Multiplexed Transcriptome and Protein Immune Profiling in Single Cells with CITE-seq: Peter Smibert, PhD, Manager, Technology Innovation The New York Genome Center