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Uncover True Genomic Heterogeneity: Getting Started with Single Cell DNA sequencing
July 30, 2019 @ 12:00 pm - 1:00 pm SGT
Genomic heterogeneity is the hallmark of many complex diseases and is characterized by cellular subpopulations with distinct genotypes and phenotypes. Standard bulk methods, such as whole-genome sequencing and whole-exome sequencing, limit our ability to accurately assess and investigate the clonal makeup in these complex diseases. Single-cell DNA sequencing is a powerful method to resolve genomic heterogeneity by building deep profiles of individual cells that otherwise get masked.
Join this webinar to:
- Learn how to detect and characterize genomic heterogeneity at high resolution by simultaneously profiling hundreds to thousands of single cells using the Chromium Single Cell CNV Solution.
- Obtain a comprehensive overview of the workflow, from nuclei preparation using frozen tissues, to single cell DNA library generation and sequencing, to analysis and visualization of genomic data at single cell resolution.
- Gain insights into experiment planning considerations and identifying the appropriate sequencing read depth.