Targeted Gene Expression
Focus on the Genes that Matter Most
Profile a defined set of transcripts from single cells or tissue sections with Targeted Gene Expression. Reduce costs while scaling up experimental throughput or increasing sequencing depth with customizable, comprehensive gene panels.
More for less
Cut sequencing costs by as much as 90%, or scale up to a 10-fold increase in sample throughput compared to whole transcriptome analysis.
Work with pre-designed panels, add genes or sequences on top, or design your own panel from scratch.
Stay on target
Don’t miss any important genes. Maximize on-target reads and minimize data volume.
Easily integrate with Feature Barcode technology and any existing gene expression libraries.
Built to scale
Easily scale sample throughput by multiplexing libraries during target enrichment.
Streamlined data analysis
Explore and interpret targeted gene expression profiles with easy-to-use software.
What You Can Do
Accelerate translational research
Move faster and inform translational studies with actionable data by focusing on clinically relevant gene expression.
Scale cellular screening
Enable genetic screens at massive scale for CAR-T cell characterization or CRISPR gene editing.
Detect and localize rare or unique cellular populations to gain deeper insights into normal development and disease pathology.
Validate biomarkers and drug targets
Use whole transcriptome analysis for discovery, then seamlessly enrich the same libraries for the most relevant genes.
Hone in on gene expression relevant to your research area. Each panel consists of validated probes for over 1,000 genes.
Add on to Pre-designed Panels
Customize pre-designed panels and add up to 200 additional genes with the 10x Genomics Custom Panel Designer. Or, if you already have a specific set of genes you want to analyze, you can create those panel designs from scratch.
How the Custom Panel Designer Works
Create an account
Design custom panels and save them to your account.
Select your panel type
Start with one of our pre-designed panels and add custom genes or design a fully custom panel.
Input custom gene list
Add up to 200 genes and 10 exogenous sequences to pre-designed panels or create a fully custom panel of 10–1,500 genes.
Review and download design files
Once you’re happy with your design, request a quote for 10x Genomics reagents and order your custom panel from our compatible partner.
Select Your Panel
Decide what genes you want to focus on. Use one of our comprehensive, pre-designed panels with or without added genes, or design from scratch with the 10x Genomics Custom Panel Designer.Resources
Coming soon: Human Neuroscience Panel
Enrich Your 10x Library
Start with an existing 10x Genomics single cell library or sequencing-ready Visium Gene Expression library from a tissue section. Perform hybrid capture with the selected gene panel to enrich for transcripts of interest.Resources
The resulting 10x Barcoded, target-enriched library is compatible with standard NGS short-read sequencing on Illumina sequencers for efficient transcriptional profiling of individual cells or tissue sections.Resources
Analyze Your Data
Convert the raw sequencing data to biologically meaningful insights with targeted analysis pipelines in Cell Ranger or Space Ranger.
Analysis pipelines output
Output includes QC information and files that can be easily used for further analysis in our Loupe visualization software, or third-party R or Python tools.Resources
Coming soon: Space Ranger 1.2
Visualize Your Data
Use Loupe Browser visualization software to interactively explore your single cell or spatial results. Perform differential gene expression analysis between clusters and samples to identify cell types, distinguishing genes, and more.
Do I need to be a bioinformatician to use it?
Loupe is a point-and-click software that’s easy for anyone to download and use.Resources