Click on the arrow to view publication on PubMed. *Pre-prints are available at BioRxiv.
Mapped the transcriptional landscape of mouse bone marrow microenvironment both at homeostasis and under conditions of stress-induced haematopoiesis revealing previously unappreciated levels of cellular heterogeneity and considerable transcriptional remodelling under stress conditions
Characterize the CD4+ T cell compartment in the human fetal intestine and found evidence for the generation of memory-like CD4+ T cells in the human fetal intestine that is consistent with exposure to foreign antigens.
Using single cell and bulk RNA sequencing, charted the evolutionary architecture of the innate immune response and found that genes that diverge rapidly between species show higher levels of cell-to-cell expression variability than genes that diverge more slowly.
Performed single-cell transcriptional profiling combined with T cell receptor sequencing in 27K T cells and characterized populations with unique combinations of clonotypes.
*Pre-prints are available at BioRxiv.