Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration

Performed multi-modal single cell and spatial profiling of a multi-region GBM patient cohort to characterize infiltrative GBM cells. This helped reveal how GBM cells hijack neurodevelopmental programs to drive brain infiltration.

Single-Cell Resolution of Individual Variation in Hypothalamic Neurons Allows Targeted Manipulation Affecting Social Motivation

Establishes proof-of-principle for an approach where single-cell genomics precisely maps neural substrates governing behavior.

Atlas-scale single-cell DNA methylation profiling with sciMETv3

Introducing sciMETv3, a combinatorial indexing-based technique that enables atlas-scale libraries to be produced in a single experiment.

MYT1L deficiency impairs excitatory neuron trajectory during cortical development

These findings illuminate MYT1L's role in orchestrating gene expression during neuronal development, providing insights into the molecular underpinnings of MYT1L syndrome.

Enhanced Single Cell DNA Methylation Analysis Using Combinatorial Indexing

Ultra high-parameter, instrument-free, protein profiling by sequencing using TotalSeq™-A antibodies at scale

Scaling Single Cell Sequencing: Multiplexing Innovations for Cost-Effective High-Throughput Profiling

Deciphering Epigenetic Landscapes: A Comparative Analysis of DNA Methylation in 2D versus 3D Cultured Colon Cancer Cells using the ScaleBio Single Cell Methylation Kit

Unlocking the potential for single cell sequencing at scale with combinatorial indexing

High-throughput robust single cell DNA methylation profiling with sciMETv2

Ultra-high throughput single cell analysis of proteins and RNAs by split-pool synthesis

Massively multiplex chemical transcriptomics at single cell resolution

High-content single cell combinatorial indexing

The single cell transcriptional landscape of mammalian organogenesis

Comprehensive single cell transcriptional profiling of a multicellular organism