Benefits of QuantumScale Single Cell RNA
Ultra-efficient Workflow
Reduce hands-on time by over 75% without any specialized instrumentation
Flexible Project Sizes
Easily scale with a range of kit sizes for proof-of-concept studies to massive projects, from 84,000 to 4 million cells
Any Sample, Any Time
Compatible across species and cells and nuclei; lock in biology with fixation until you're ready to run
Simplified Multiplexing
Easily combine 10 to >9,000 samples or conditions in a single run and eliminate batch effects with ScalePlex
Your Budget Goes Further
The most cost-effective solution on the market per cell, sample and experiment
Performance Maximized
High sensitivity and achieve cell recovery of 50%–60% or higher, while keeping multiplets low (≤4%)
One solution for every scale
Your boldest projects, now possible. The most samples, now simpler than ever.
Kit type
Medium Kit
Cells analyzed
Up to 168K
Ideal for
Projects with multiple timepoints or conditions, multi-site studies, processing biobanked specimens
Kit type
Large Kit
Cells analyzed
Up to 2M
Ideal for
Drug perturbation or screening projects, population and cohort studies, foundational models for AI, other large-scale projects
Kit type
Extra Large Kit
Cells analyzed
Up to 4M
Ideal for
Drug perturbation or screening projects, population and cohort studies, foundational models for AI, other large-scale projects
Key advantages
Quantum Barcoding technology dramatically streamlines your workflow
Quantum Barcode technology consolidates many levels of barcoding into one streamlined operation, cutting hands-on time by over 75%.
High performance for every scale
- Maximize insights with high transcript sensitivity
- Achieve cell recovery of 50%–60% or higher while keeping multiplets low (≤4%)
- Run projects of varying sizes with confidence using the same underlying technology
Lab efficiency for every scale
- Go from sample to sequencer-ready library for any sized project in 1.5 days
- Whether you are processing a few or thousands of samples, only half a day of hands-on time
- Easily scale projects with minimal increase in workflow time
One streamlined workflow for every scale
Our comprehensive QuantumScale Single Cell RNA Sequencing workflow includes optimized sample fixation, library preparation using Quantum Barcoding technology, and integrated data analysis to power your research insights — all without requiring specialized equipment.
Effortless sample multiplexing for every scale
- Profile thousands of samples per run using ScalePlex
- No upfront optimization and compatible across species and cells or nuclei
- Simultaneously fix and label up to 96 samples in parallel, saving hours of time
- Minimize sample loss with fewer processing steps
Choose the QuantumScale kit for your project
| Kit size | Medium | Large | Extra Large |
| Method | 3’ Whole Transcriptome | 3’ Whole Transcriptome | 3’ Whole Transcriptome |
| Number of samples at 10k cells/sample | 16 | 200 | 400 |
| Project run size (cells) | 168K | 2M | 4M |
| Consider this kit for | Standard-sized projects Biobanked specimens | Time-course or multi-site studies Biobanked specimens | Time-course or multi-site studies Biobanked specimens |
| Sample types | Cells, nuclei, frozen tissue, OCT-embedded samples · Any species | Cells, nuclei, frozen tissue, OCT-embedded samples · Any species | Cells, nuclei, frozen tissue, OCT-embedded samples · Any species |
| Sample number | 1–24 | 1–96 | 1–96 |
| Sample number with ScalePlex | Up to 2,304 | Up to 9,216 | Up to 9,216 |
| Compatible flowcells | NovaSeq X - 1.5B or 10B UG 100™ | NovaSeq X - 25B UG 100™ | NovaSeq X - 25B UG 100™ |
Frequently asked questions
- What types of samples are compatible?
- We have demonstrated performance across a broad range of sample types, including but not limited to: tissue-dissociated cells, nuclei isolated from frozen and fresh tissues, PBMCs, and cell lines.
- How long can samples be stored after fixation?
- After fixation, samples can be stored immediately at -80°C or transported on dry ice and then stored at -80°C. Current tested storage recommendation is up to 1 year.
- How do I multiplex samples?
- Samples can be fixed individually or fixed and pooled with ScalePlex oligos for streamlined multiplexing. Samples or ScalePlex pools can be processed immediately or stored for future use. When ready to start the library preparation, each sample or sample pool can be distributed across multiple RT wells for deeper profiling, or one RT well for maximum sample throughput.
- What data analysis software is available?
- Scale Bio provides a data analysis pipeline, the Scale Bio SeqSuite, which is compatible with sequencing instrument output files. The pipeline will de-multiplex samples, generate a cell-gene matrix, and provide a data quality metrics summary to assess run performance. The output files are compatible with many community software tools, including Seurat.
- What sequencers are compatible?
- QuantumScale Single Cell RNA Sequencing libraries have been demonstrated with Illumina's NextSeq and NovaSeq instruments, and Ultima Genomics' UG 100™.
- Are public data sets available?
- Yes, you can access our public data sets on the Datasets page.