List of human and mouse tissue types that were tested in-house with Xenium Prime In Situ Gene Expression. These include both fresh frozen and FFPE samples. FFPE tissues tested in-house were acquired from biobanks. Additional information about 10x Genomics Xenium Prime pre-designed panels is available here.
Please note: sample preparation variability (such as fixation and embedding techniques), tissue biology, and slide handling may impact assay performance. In addition, disease state and presence of add-on panels may impact assay performance. All tissues listed below were processed per our standard documentation (CG000760).
The Xenium Prime In Situ Gene Expression with Cell Segmentation Staining workflow were tested on the same tissues listed on the Multimodal Cell Segmentation Validated Tissue List page.
Some tissues were tested with multiple tissue states. Select datasets can be found here.
Human tissue types
| Tissue | Tissue States |
|---|---|
| Brain | Non-diseased, Glioblastoma |
| Breast | Non-diseased, Cancer |
| Colon | Normal adjacent |
| Eye | Non-diseased |
| Kidney | Non-diseased, Cancer, Renal Cell Carcinoma |
| Liver | Non-diseased, Hepatocellular Carcinoma |
| Lung | Non-diseased |
| Lymph Node | Lymphoma |
| Ovary | Non-diseased, Adenocarcinoma |
| Pancreas | Ductal Adenocarcinoma |
| Prostate | Adenocarcinoma |
| Skin | Non-diseased, Melanoma |
Mouse tissue types
| Tissue | Tissue States |
|---|---|
| Brain (sagittal and coronal) | Non-diseased |
| Colon | Non-diseased |
| Heart | Non-diseased |
| Ileum | Non-diseased |
| Kidney | Non-diseased |
| Liver | Non-diseased |
| Lung | Non-diseased |
| Skin | Non-diseased |
| Small Intestine | Non-diseased |
| Spleen | Non-diseased |
| Whole neonatal mouse (sagittal) | Non-diseased |