Atera Onboard Analysis

Cell Ranger ARC

Chromium

Gene Expression

Epigenomic Profiling

Immune Profiling

Protein co-detection

Simultaneously profile gene expression and open chromatin from the same cell with Chromium Single Cell Multiome ATAC + Gene Expression. Multiply your power of discovery to characterize cell types and states, and uncover gene regulatory programs.

Unify the transcriptome and epigenome in every cell

Chromium X Series

Advanced system for multiomic analysis of hundreds to millions of cells.

Single Cell Multiome ATAC + Gene Expression

Combined profiling of 3' gene expression and chromatin accessibility from the same cell.

Analyze Epi Multiome data with a set of free, easy-to-use pipelines for primary and secondary analyses.

Cell Ranger ATAC

Chromium Single Cell ATAC (Assay for Transposase Accessible Chromatin) allows you to analyze chromatin accessibility at the single cell level, providing insights into cell types and states, and deeper understanding of gene regulatory mechanisms. 

Reveal the epigenomic landscape, cell by cell

Single Cell ATAC

Chromatin accessibilility profiling at the single cell level.

Analyze Epi ATAC data to identify open chromatin regions, motif annotation, and differential accessibility.

Cell Ranger DNA

Cell Ranger VDJ

Chromium Single Cell Immune Profiling provides a multiomic solution to your immunology questions. Analyze full-length V(D)J sequences for paired B-cell or T-cell receptors, cell surface protein expression, antigen specificity, and/or CRISPR edits, along with gene expression, all from a single cell.

Cell Surface Protein

Antigen Specificity

CRISPR Screening

Multiomic profiling of immune diversity, cell by cell

Single Cell Immune Profiling

5' gene expression alongside V(D)J repertoire profiling and antigen specificity of T and B cells.

Analyze single cell gene expression and V(D)J transcripts and clonotypes for T and B cells.

Cell Ranger

Chromium Single Cell Gene Expression provides single cell transcriptome 3' gene expression and multiomic capabilities to profile tens of thousands of cells. Explore cellular heterogeneity, novel targets, and biomarkers with combined gene expression, cell surface protein expression, or CRISPR edits in each cell.

Sample multiplexing

Reveal the full complexity of cellular diversity, cell by cell

Single Cell Gene Expression

3' gene expression profiling at scale with single cell resolution.

Profile a defined set of transcripts from single cells or tissue sections with Targeted Gene Expression. Reduce costs while increasing the number of samples, or increasing sequencing depth with customizable, comprehensive gene panels.

Discontinuation of Targeted Gene Expression

Chromium Connect

Automated system for single cell partitioning, barcoding, and library preparation.

Chromium Controller

Compact system for multiomic analysis of hundreds to tens of thousands of single cells.

Targeted Gene Expression

Visium

Profiling of defined transcript sets from single cells or fresh frozen tissue sections.

Analyze single cell gene expression data with a set of free, easy-to-use analysis pipelines.

10x Genomics Cloud Analysis is a platform for data management, analysis, and collaboration to streamline and accelerate the interpretation of data generated from 10x Genomics assays.

Data analysis,
simplified

Cloud Analysis

Analyze 10x Genomics data quickly and securely in the cloud.

Panel Designer

Build fully custom Targeted Gene Expression panels or customize pre-designed panels.

Long Ranger

Loupe Browser is a powerful visualization software that provides intuitive analysis functionality you need to explore your 10x Genomics data. This easy-to-use desktop application for Windows and MacOS is available at no cost, enabling anyone to uncover biological insights from their data.

From data to biological insights

Loupe Browser

Visium Spatial Gene Expression is a next-generation molecular profiling solution for classifying tissue based on total mRNA. Map the whole transcriptome with morphological context in FFPE or fresh frozen tissues to discover novel insights into normal development, disease pathology, and clinical translational research.

Immunofluorescence protein co-detection

Visium CytAssist Gene and Protein Expression

Map the whole transcriptome within the tissue context

Visium CytAssist

Compact instrument designed to simplify the Visium workflow by facilitating the transfer of analytes from standard glass slides to Visium slides.

Spatial Gene Expression

Spatial gene expression profiling and imaging data of fresh frozen or FFPE tissues.

Explore 10x Genomics Chromium and Visium data with our interactive visualization software.

Loupe V(D)J Browser

Investigate single cell 5' data clonotypes and V(D)J transcripts with our interactive visualization software.

Space Ranger

Analyze your Visium Spatial data with microscope images.

Supernova

Explore Xenium In Situ data from the tissue scale down to subcellular resolution with our interactive visualization tool.

Xenium Explorer

Xenium

Xenium Onboard Analysis

Our diverse panel menu of pre-validated biologically relevant targets can be customized with up to 100 additional targets. Standalone custom panels can also be designed for your specific research questions.

Expertly curated, easily customizable in situ panels

Xenium Analyzer

Powerful in situ profiling platform using curated panels, powerful visualization software, and easy-to-follow workflow.

In Situ Gene Expression

Enables subcellular profiling of 100s of RNA targets from Fresh Frozen or FFPE tissues.

Details about the algorithms and output files for Xenium In Situ data.

Xenium Panel Designer

Submit custom panel requests in the cloud.

Xenium Ranger

Analyze Xenium In Situ data with a set of easy-to-use analysis pipelines.

Flex Gene Expression enables single cell gene expression on precious samples that were previously inaccessible due to logistical challenges in sample handling. Fixation at the point of sample collection preserves fragile biology and greatly streamlines workflows to provide critical insights on more samples.

Reveal gene expression and protein expression from the same fixed cell.

Flex with Protein Labeling

Protein

It is critical to choose the User Guide / Protocol that corresponds to your Reagent Kit version. Find the right User Guide via the button below.

10x PAE Services are designed to help you automate your workflows with confidence.

Premium Automation Enablement (PAE)

Additional Applications

Measure single cell gene and cell surface protein expression simultaneously.

Find resources from protocols to free-to-use analysis tools.

Plate-based sample handling brings unprecedented scale to highly sensitive single cell profiling

Flex

Fixed RNA Profiling assay for comprehensive probe-based gene expression profiling with single cell resolution.

Plan ahead by referring to the list of equipment, kits, and reagents needed for Flex Gene Expression.

Experimental Design

Experimental Design & Planning

Prepare single cell/nuclei suspension from fresh samples for fixation or from archived samples by following our Demonstrated Protocols.

Sample Prep

Find a list of probes targeting protein-coding genes for the Flex assay.

Probe Sets

Construct a sequencing-ready single cell library by following our step-by-step User Guide / Protocol.

Library Construction

Refer to instrument-specific documents for seamless instrument operation.

Instruments

Sequence your single cell or nuclei library as per our provided recommendations.

Sequencing

Analyze your genome and exome data using our pipelines and visualization tools.

Software Analysis

Workflow Documentation

Overview

User Guides

Datasets

Videos

Flex Gene Expression

What is Flex Gene Expression?

Access free, publicly available data from a number of different sample types generated with Chromium single cell solutions.

GEM-X: How to assemble, load and generate GEMs

Chromium Next GEM Tissue Fixation and Dissociation

Chromium Next GEM Single Cell Isolation from FFPE Sections

Find answers to common technical questions, from sample prep through data analysis, about the Flex Gene Expression workflow.