Jul 30, 2019

Visium Spatial Scientific Challenge

Kariena Dill

The relationship between cells and their organization within tissue is critical to understanding normal development and disease pathology. The Visium Spatial Gene Expression Solution, launching later this year, allows for the investigation of spatially resolved whole transcriptome mRNA expression, while capturing histological information in the same tissue section. Using this solution, gene expression profiles can be mapped back to their original location, providing an unprecedented view of tissue and gene expression complexity as it applies to the study of cancer, immuno-oncology, neuroscience, developmental biology, and beyond.

Already, advances in spatial transcriptomics technologies have lead to new discoveries that will prove instrumental in helping scientists gain a better understanding of biological processes and disease, but we want to hear from you. 10x Genomics is inviting researchers to share their innovative ideas for Spatial Gene Expression experiments for a chance to win a project performed by 10x Genomics (sample prep, library prep, sequencing, and data analysis).

Challenge Details
Submit an abstract (maximum of 300 words) proposing a project that uses the upcoming Visium Spatial Gene Expression Solution. This solution provides an unbiased, whole transcriptome approach to layering gene expression data onto tissue morphology validated on fresh-frozen tissue samples. Please specify the question you are hoping to answer, how this technology will help you, the sample types used, the number of tissue sections (max 8) being studied, and how the results will inform your future studies. A 10x Genomics committee will review and select the winner based on research creativity, scientific impact, and innovation.

10x Genomics will process the selected winner’s samples through the Visium Spatial Gene Expression assay workflow, sequence, and provide data analysis.