Visium空间分析

全转录组空间发现

灵活的分析,满足您的不同需求

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概览

HD WT Panel基因表达

覆盖蛋白编码基因

  • 在研究人类和小鼠的差异基因表达时推荐使用

  • 灵活的组织兼容性

  • 测序效率极高的Visium HD分析

HD 3’基因表达

覆盖全转录组

  • 适用于扩展型发现应用的推荐检测方法

  • 广泛的物种兼容性

  • 支持从头发现,包括异构体、TCR/BCR等

化学方法

Probe-based
3' poly(A) capture-based (Reverse transcription)

兼容物种

Human
Mouse
Rat
Agnostic

兼容样本

FFPE tissue
Fresh frozen tissue
Fixed frozen tissue
Fresh frozen tissue

起始样本

Tissues sectioned onto glass slides
Tissues sectioned onto glass slides

玻片结构和分辨率

Continuous lawn of 2 μm x 2 μm barcoded squares for single cell–scale resolution

Continuous lawn of 2 μm x 2 μm barcoded squares for single cell–scale resolution

捕获区域大小

6.5 x 6.5 mm (2 Capture Areas per slide)
11 x 11mm(每张玻片2个捕获区域)
6.5 x 6.5 mm (2 Capture Areas per slide)

同一组织切片上的多重分析能力

Gene expression
Protein (IF)
Morphology (H&E)
Gene expression
Morphology (H&E)

专题资源

入门资源

空间产品购买指南(即将发布)

Explore the unique strengths and applications of the 10x spatial portfolio, plus compare and contrast the Visium and Xenium platforms to find the right fit for your needs.

经费申请资源

Get the information you need to write grants featuring Visium experiments (including a technology overview, benchmarking data, and more).

用户指南

Find helpful user guides and technical documents to get started with Visium HD spatial assays.

精选文献

Systematic benchmarking of high-throughput subcellular spatial transcriptomics platforms (bioRxiv, Dec 2024 Ren P et al.)

Demonstrated the Visium HD assay has superior spatial fidelity compared to other commercially available sequencing-based spatial transcriptomics platforms.

Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted (Nature, Jan 2025 Reina-Campos M et al.)

Discovered that regionalized signalling drives two distinct T-cell states in the small intestine.

查看所有文献

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