Visium空间分析

全转录组空间发现

Chromium Single Cell
灵活的分析,满足您的不同需求

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概览
Visium HD icon

HD WT Panel基因表达

覆盖蛋白编码基因

  • 在研究人类和小鼠的差异基因表达时推荐使用
  • 灵活的组织兼容性
  • 测序效率极高的Visium HD分析
Visium HD 3' icon

HD 3’基因表达

覆盖全转录组

  • 适用于扩展型发现应用的推荐检测方法
  • 广泛的物种兼容性
  • 支持从头发现,包括异构体、TCR/BCR等
产品
化学方法
  • Probe-basedProbe-based
  • 3' poly(A) capture-based (Reverse transcription)3' poly(A) capture-based (Reverse transcription)
兼容物种
  • HumanHuman
  • MouseMouse
  • AgnosticAgnostic
兼容样本
  • FFPE tissueFFPE tissue
  • Fresh frozen tissueFresh frozen tissue
  • Fixed frozen tissueFixed frozen tissue
  • Fresh frozen tissueFresh frozen tissue
起始样本
  • Tissues sectioned onto glass slides
  • Tissues sectioned onto glass slides
玻片结构和分辨率
  • Continuous lawn of 2 μm x 2 μm barcoded squares for single cell–scale resolutionContinuous lawn of 2 μm x 2 μm barcoded squares for single cell–scale resolution
  • Continuous lawn of 2 μm x 2 μm barcoded squares for single cell–scale resolutionContinuous lawn of 2 μm x 2 μm barcoded squares for single cell–scale resolution
捕获区域大小
  • 6.5 x 6.5 mm (2 Capture Areas per slide)
  • 6.5 x 6.5 mm (2 Capture Areas per slide)
同一组织切片上的多重分析能力
  • Gene expressionGene expression
  • Protein (IF)Protein (IF)
  • Morphology (H&E)Morphology (H&E)
  • Gene expressionGene expression
  • Morphology (H&E)Morphology (H&E)

First-generation assays

v2 WT Panel基因表达 assay icon

v2 WT Panel基因表达

覆盖蛋白编码基因

  • 基于探针的化学方法,适用于人类和小鼠的FFPE、新鲜冷冻和固定冷冻组织
  • 多组学选项,提供以免疫肿瘤学为重点的蛋白检测组合
  • 每个55 µm条形码标记捕获点的分辨率为1-10个细胞
V1 3’基因表达 assay icon

V1 3’基因表达

覆盖全转录组

  • 基于3’ poly(A)捕获的化学方法,适用于广泛物种的新鲜冷冻组织
  • 每个55 µm条形码标记捕获点的分辨率为1-10个细胞

入门资源

Spatial Buyer's Guide

空间产品购买指南(即将发布)

Explore the unique strengths and applications of the 10x spatial portfolio, plus compare and contrast the Visium and Xenium platforms to find the right fit for your needs.

User Guides

用户指南

Find helpful user guides and technical documents to get started with Visium HD spatial assays.

精选文献

View all publications

Systematic benchmarking of high-throughput subcellular spatial transcriptomics platforms

Demonstrated the Visium HD assay has superior spatial fidelity compared to other commercially available sequencing-based spatial transcriptomics platforms.

bioRxiv, Dec 2024

Ren P et al.

Read on bioRxiv

Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling

Mapped critical immune cell interactions in the colorectal tumor microenvironment.

bioRxiv, Jun 2024

Oliveira MF et al.

Read on bioRxiv

Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted

Discovered that regionalized signalling drives two distinct T-cell states in the small intestine.

Nature, Jan 2025

Reina-Campos M et al.

Read on PubMed

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