Support home
Epi Multiome
Chromium Single Cell

Epi Multiome

GEM-X Epi Multiome requires Chromium X/iX instrument Firmware v2.0 or newer. Refer to the Chromium X Series Firmware Update Procedure for details
product-intro
What is Epi Multiome?

Chromium Epi Multiome performs direct measurements of 3' gene expression and chromatin accessibility from the same nucleus.

Find user guidesGet started

Workflow Documentation

We provide resources from Demonstrated Protocols, User Guides, and free-to-use analysis tools.

Experimental Design & Planning

Plan ahead by referring to the list of equipment, kits, and reagents needed for Epi Multiome.

Sample Prep

Prepare optimal single cell/nuclei suspensions by following our Demonstrated Protocols or Sample Prep User Guide.

Instruments

Refer to instrument-specific documents for seamless instrument operation.

Library Construction

Construct a sequencing-ready single cell library by following our step-by-step User Guide / Protocol from nucleus samples.

Sequencing

Sequence your single nucleus library as per our provided recommendations.

Software Analysis

Analyze your single nuclei data using our pipelines, visualization, and Cloud Analysis tools.

Datasets

Access free, publicly available data from a number of different sample types generated with Chromium single cell solutions.

View datasets
Datasets

Videos

GEM-X: How to assemble, load and generate GEMs video
How-to series
GEM-X: How to assemble, load and generate GEMs
Chromium Single Cell Multiome ATAC and Gene Expression video
Training Module
Chromium Single Cell Multiome ATAC and Gene Expression
Chromium Next GEM Epi Multiome video
How-to series
Chromium Next GEM Epi Multiome
View all videos
Q&A

Find answers to common technical questions, from sample prep through data analysis, about Chromium single cell workflows.

Q&A
Publications

Read key peer-reviewed research publications offering greater insights into biology, enabled by 10x Genomics products and technologies.

Publications