Exceptional spatial performance
Superior spatial data quality, faster time to results

The Xenium platform consistently delivers
More transcripts on shared genes
Better spatial resolution and discrimination of cell types
Greater specificity and lower background noise
Higher consistency with orthogonal benchmarking

Xenium 5K exhibited the most distinct expression patterns, facilitating more accurate cell type annotations.Ren et al.Source: Ren et al. (2024) courtesy of Dr. Zexian Zeng, Peking University.
Industry-leading speed & throughput


Ultimate versatility, streamlined workflows
Unmatched customization
Easily customize pre-designed panels with up to 100 genes, or design fully custom panels of up to 480 genes, with the Custom Panel Designer
Go from design to delivered in just 4–6 weeks
Tailor your order size to fit your experiment and your budget, with sizes as small as 4 reactions
Take advantage of advanced custom services to add TCR/BCRs, isoforms, SNVs, xenografts, and viral/bacterial sequences onto your panels
The Xenium platform is the only high-plex single cell spatial transcriptomics solution capable of detecting TCR/BCR sequences, isoforms, and SNVs due to its proprietary padlock probe chemistry
See the custom panels in action

Custom probes identify spatial localization of specific SNVs
Image adapted from Figure 2E of Ding et al. 2024.

100-gene custom panel maps spatial development of maize
Image adapted from Figure 3 of Wu et al. 2025.

Custom viral probes detect Hepatitis B RNA with high sensitivity
Data provided courtesy of Nadina Wand and Jane McKeating, University of Oxford and Kings College Hospital, London.
A universal tissue-agnostic workflow saves time and samples

One sample prep workflow - Avoid the headaches of optimizing conditions on a per-tissue basis
One cell segmentation stain mix - Eliminate the need to select stain mixes for each tissue type
One comprehensive panel menu - Access the industry’s largest menu of off-the-shelf panels with >10 human and mouse options, ranging from 100s to 1,000s of genes
Maximize insights, minimize headaches
Interpretable data ready immediately after a run

Optimized data analysis without the hassle
10x Genomics Xenium software
Provides free-of-charge analysis and visualization
Delivers interpretable data as soon as the run is complete
Outputs unified tissue images, making it easy to pan and zoom through the entire sample image
Enables easy overlay of H&E and IF images with gene expression data
Expedites panel customization with an intuitive Custom Panel Designer
Other in situ platform software
Requires annual license fees after the first year
Requires data transfer and analysis via the cloud before data can be viewed
Outputs analysis per field of view (FOV) and requires FOV stitching, which may lead to edge artifacts [1]
Lacks the ability to register H&E or IF images within the software
No self-serve custom panel design capabilities
Your partner from tissue to insight
We’re here to help. Leverage our comprehensive resources and training to help you succeed, or reach out to us for more personalized assistance.
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