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The Immune Cell Landscape in Kidneys of Patients With Lupus Nephritis

The Immune Cell Landscape in Kidneys of Patients With Lupus Nephritis

Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and the University of Michigan performed single cell analysis of immune cells in human kidneys affected by lupus nephritis. They identified 21 subsets of leukocytes active in disease, and noted heightened expression of two chemokine receptors that may be involved in cell trafficking.

Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and the University of Michigan performed single cell analysis of immune cells in human kidneys affected by lupus nephritis. They identified 21 subsets of leukocytes active in disease, and noted heightened expression of two chemokine receptors that may be involved in cell trafficking.