Visium Spatial Platform

Whole transcriptome spatial discovery

Best-in-class spatial data quality with complete coverage

The Visium platform delivers unbiased, whole transcriptome spatial gene expression analysis at single cell scale with unmatched spatial data quality and offers a flexible assay portfolio to study a broad range of tissues.
10x Genomics Visium platform

Visium slides and reagents

High-resolution, whole transcriptome spatial gene expression across species and tissue conditions

Visium CytAssist instrument

Enables a histology-friendly workflow and provides high spatial fidelity

Data analysis

Free, easy-to-use software for intuitive data visualization and exploration

Visium HD Human Tonsil
NOW SHIPPING! Visium HD 3'

Deeper spatial discovery

  • Species-agnostic, whole transcriptome spatial analysis at single cell–scale resolution with cell segmentation

  • De novo discovery, including feasibility for isoform, TCR/BCR, and SNV detection

  • High spatial fidelity and a streamlined, histology-friendly workflow powered by the Visium CytAssist instrument

Whole transcriptome spatial biology at the resolution you need

Our Visium HD product line offers a distinct slide architecture and two chemistries to explore the whole transcriptome spatial biology of your samples at the resolution you need.

Visium HD WT Panel

Recommended for differential gene expression in human and mouse

  • Protein coding gene coverage: Optimized for archival and FFPE samples

  • Flexible tissue compatibility: Compatible with FFPE, fresh frozen, and fixed frozen tissues

NEW! Visium HD 3'

Recommended for expanded discovery applications

  • Whole transcriptome coverage: Delivers de novo discovery power

  • Explore across species: Tested in human, mouse, rat, pig, non-human primate and more.

Unmatched spatial data quality with a histology-friendly workflow

  • Ensure high spatial fidelity through precise transcript localization facilitated by the Visium CytAssist instrument

  • Leverage a standard histological workflow to section, stain, and image tissues directly on glass slides

  • Pre-screen and orient tissue sections to align the most desired region of tissue onto the Capture Area of the Visium slide

Accelerate spatial discovery with intuitive data exploration

Simple, fast analysis with Space Ranger

  • Upload FASTQ files to 10x Cloud Analysis or download our free software for local analysis

  • Process spatial sequencing data with imaging data in minutes with no command line required, including cell segmentation

Learn more about Space Ranger

Immediate insights with powerful data visualization

  • Visualize and explore thousands of spatially variable genes in a few clicks with Loupe Browser

  • Explore gene expression clusters in the tissue context to define cell types or gene signatures by region and morphology

Learn more about Loupe Browser

Resources

See Visium HD data in action

Learn how to map the tumor microenvironment of colorectal cancer with the Visium HD assay and Loupe Browser in this guided data tutorial.

Grant writing assistance

Get the information you need to write grants featuring Visium experiments (including technology overview, benchmarking data, and more).

Spatial publications

Browse peer-reviewed publications to see how researchers have used Visium Spatial technology to accelerate novel discoveries.

Unlock the full spectrum of biology

Elevate your Visium Spatial insights with comprehensive single cell analysis or targeted, precision insights into the tissue context.See how researchers used Chromium, Visium, and Xenium assays to study human lung development
Platform
Chromium Single Cell platform

Chromium Single Cell platform

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Visium Spatial platform

Visium Spatial platform

See Visium HD assays
Xenium Spatial platform

Xenium Spatial platform

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When to use
Comprehensive single cell dataIdeal for deep characterization of cell populations and states.
High-resolution spatial gene expressionUnderstand complex tissues, neighborhoods, and cell to cell interactions. Integration with other spatial-omics, histology, and morphology.
Why to use
Unbiased single cell discovery High per-gene sensitivity
Unbiased spatial discovery
Targeted spatial exploration High per-gene sensitivity
Applications
Whole transcriptome gene expression Protein TCR, BCR CRISPR ATAC
Whole transcriptome gene expression
Targeted gene expression (up to 5,000 genes)
Resolution
Single cell
Transcripts assigned to 2-µm areas
Single cell
Data readout
NGS-based
NGS-based
Imaging-based
Sample compatibility
Single cell or nuclei suspensions from fresh, frozen, or FFPE samples
FFPE Fresh frozen Fixed frozen
Fresh frozen FFPE

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