Visium Spatial

Whole transcriptome discovery in the tissue context

Speak to a specialist
Read Visium HD preprint
10x Genomics Visium platform

Now compatible with fresh frozen, fixed frozen, and FFPE

Introducing a new era of spatial discovery with Visium HD Spatial Gene Expression

  • Whole transcriptome analysis at single cell-scale resolution
  • Continuous tissue coverage
  • Best-in-class data powered by innovative probe-based chemistry and a Visium CytAssist-enabled workflow
See your tissue in HD

Insights from spatial profiling in action

See how whole transcriptome spatial analysis has helped researchers identify cell types and cell–cell interactions that drive crucial functions in health and disease.

Assays

Flexible assays that suit your needs

Assay

HD Spatial Gene Expression

HD Spatial Gene Expression
Learn moreOrder now

Spatial Gene Expression v2 & v1

Spatial Gene Expression v2 & v1

Spatial Gene + Protein Expression

Spatial Gene + Protein Expression

What you can do

Proven whole transcriptome spatial analysis at single cell-scale resolution and continuous tissue coverage.

  • Whole transcriptome

Simultaneous analysis of molecular and imaging data from FFPE & frozen tissue sections.

  • Whole transcriptome

Simultaneous analysis of RNA and protein expression of FFPE tissues, using probe-based chemistry and tagged antibodies.

  • Whole transcriptome
  • Protein expression

Species compatibility

Human and mouse

Various

Human and mouse

Tissue compatibility

FFPE

fresh frozen

fixed frozen

FFPE

fresh frozen

fixed frozen

FFPE

Capture Area size

6.5 mm x 6.5mm

6.5 mm x 6.5 mm

11 mm x 11 mm

6.5 mm x 6.5 mm

11 mm x 11 mm

Analyte capture method

  • CytAssist enabled, probe-based chemistry
  • CytAssist enabled, probe-based chemistry (for FFPE, fresh frozen, and fixed frozen)
  • Direct Placement, PolyA capture-based chemistry (for fresh frozen)
  • CytAssist enabled, probe-based chemistry (for FFPE)
  • Visium CytAssist

    Simple sample handling and powerful spatial insights

      1
    1. Start with typical histology workflow on standard glass slides
    2. 2
    3. Use the instrument to transfer slides to Visium capture areas
    4. 3
    5. Proceed with the remaining Visium workflow
    Discover the CytAssist
    See how it works
  • Visium CytAssist instrument
  • Analysis software

    An intuitive visual canvas for your spatial analysis

    Explore spatial analysis software

    Transform sequencing data into gene expression-aligned images

    Map the whole transcriptome across your tissue sections with Space Ranger, a set of analysis pipelines that process sequencing data with brightfield and fluorescence microscope images.

    Dive into your data and uncover new spatial biology insights

    Explore your Space Ranger results using Loupe Browser. Loupe Browser is a desktop application that enables you to easily navigate through molecular expression patterns overlaid on your original tissue section image.

    Resources

    Explore the power of spatial biology

    Enhance your spatial discovery with complementary platforms

    Expand your Visium insights by interrogating single cell profiling with newly discovered mapped cell types or deepen your understanding of specific targets using Xenium subcellular precision.

    • 10x Genomics Chromium Single Cell Platform

      Perform transcriptomic profiling, with multiomic capabilities, in up to a million single cells

      Characterize tissue heterogeneity, discover rare cell types, and dissect molecular mechanisms cell by cell.

    • image

      Target 100’s to 1000’s of RNAs in individual cells across a tissue sample

      Map gene expression at subcellular resolution with a diverse menu of validated, biologically relevant panels

    Start your Visium journey

    Speak to a specialist