Visium CytAssist

Bridging histology and genomics

View Pricing

Visium CytAssist instrument

Resources:

  • Choice

    Start from FFPE blocks or pre-sectioned tissue on glass slides.

  • Confidence

    Pre-screen to find the most biologically relevant tissue sections.

  • Flexibility

    Integrate seamlessly with standard histology workflows for H&E and IF staining.

Simplified sample processing

  • The Visium CytAssist is a compact instrument designed to simplify the Visium workflow by facilitating the transfer of transcriptomic probes from standard glass slides to Visium slides, enabling spatial profiling insights to be gained from an expanded range of FFPE samples.
    CytAssist instrument with labeled dimensions, 10" x 8" x 12"
  • Simplified sample management

    It all starts with a standard glass slide. The Visium CytAssist enables users to start with tissue on standard glass slides, allowing input tissue to be prepared, stained, and imaged using standard histology workflows.

  • Expanded sample access

    Compatible with H&E or immunofluorescently stained FFPE tissue sections, the CytAssist instrument allows you to use pre-sectioned and pre-stained tissues with 6.5 x 6.5 mm or 11 x 11 mm Visium Capture Area slides.

  • Maximized spatial insights

    Pre-screen tissue sections and then use the instrument for precise manual alignment of tissue section to Visium Capture Areas making the most of your spatial discovery studies.

Visium workflow with CytAssist

Visium for FFPE workflow, including transfer of sample from standard glass slide to Visium slide using CytAssist

Facilitate transfer of transcriptomic analytes in FFPE samples with Visium CytAssist. In the Visium CytAssist workflow, sectioning, deparaffinization, and staining and imaging (H&E or IF) take place on a standard glass slide. After probe hybridization, two standard glass slides and a two–Capture Area Visium slide are placed in the CytAssist instrument so that the tissue sections on the standard slides can be aligned on top of the two Visium Capture Areas. Within the instrument, a brightfield image is captured to provide spatial orientation for data analysis, followed by hybridization of transcriptomic probes to the Visium slide. The remaining steps, starting with probe extension, follow the standard Visium for FFPE workflow outside of the instrument.

Visium CytAssist

A compact instrument to facilitate the transfer of analytes from sectioned tissues to Visium Slides.

Visium gene expression reagents

Compatible with Visium Spatial Gene Expression for FFPE.

Data visualization software

Our analysis pipelines

Our visualization software

World-class technical and customer support

Contact our support team by phone or email.

Frequently Asked Questions

Visium CytAssist enables access to FFPE samples archived in blocks or pre-sectioned onto standard glass slides. Existing samples can be stained with H&E staining or IF antibodies on the glass slides before introduction to the Visium workflow.

The CytAssist will be compatible with human and mouse FFPE samples.

Bridge histology and genomics with Visium CytAssist