A Guide to Leveraging Single-Cell CRISPR Screens for Deeper Biological Insights with 10x Genomics and MilliporeSigma

Study the complexity of development, disease, gene function, and therapeutic response at single cell resolution. Single cell CRISPR screens enable scalable, comprehensive readouts of cellular phenotypes directly assessing both the specific CRISPR-driven gene edits or knockdowns and the resulting perturbed phenotypes, including gene expression and cell surface proteins.

Functional genomics at <em>single cell resolution</em>

Chromium X Series

Chromium

Advanced system for multiomic analysis of hundreds to millions of cells.

Chromium Connect

Automated system for single cell partitioning, barcoding, and library preparation.

Chromium Controller

Compact system for multiomic analysis of hundreds to tens of thousands of single cells.