Understanding of Innate
and Adaptive Immunity
Uncover the Layers
of Immune Cell Complexity
Addressing the intricacies of the immune system leads to actionable insight into infectious disease, autoimmune disorders, immunotherapy development, and cancer. Learn how you can explore immunology with unprecedented breadth, depth, and precision to truly change the course of human health using 10x Genomics technology.
Beyond the Surface
Learn more about how to further the study of infectious disease, autoimmunity, and cancer with single cell sequencing tools, multiomics, and beyond. Download our immunology research guide to take your research to the next level and comprehensively characterize innate and adaptive immunity.Download
10x-pert Workshop: A New Way of Exploring Immunity
How will you explore immunology with unprecedented breadth, depth, and precision to truly change the course of human health? In this workshop, you will hear from 10x Genomics’ scientists about:
- Generating data at single cell resolution from over 150,000 CD8+ T cells from 4 human donors across a highly multiplexed panel of 44 distinct, specific peptide–MHC (pMHC) multimers
- Uncovering gene and cell surface protein expression, TCR-pMHC binding specificity, and paired alpha/beta T-cell receptor (TCR) sequences from the same single cell
- Facilitating a greater understanding of how the adaptive immune system responds to immune insults and contributing to the development of therapeutics
Jul 10, 2019 | 9am PST
Advance immunotherapy development by fully characterizing the immune response. Define the genetic repertoire of immune cells and reveal novel TCR-antigen relationships. Identify clonal expansions, peripheral blood markers and measure T-cell exhaustion.
Profile diverse cell states involved in autoimmunity and study disease mechanisms for autoimmune disorders. Understand how TCR specificity influences T-cell function. Elucidate the mechanisms involved in autoimmunity development.
Better understand the immune response and pathogenicity of disease to pave the way for therapeutic development. Define the genetic repertoire of immune cells and reveal novel TCR-antigen binding to understand T-cell function.
Dissect cellular heterogeneity to understand the complex interactions between tumor cells and tumor infiltrating lymphocytes (TILs). Get new insights into tumor immunology by coupling gene expression data with matched, paired clonotypes.
Capture a Holistic Snapshot of the Immune System
Gain the flexibility to perform immunology research the way you want. Comprehensive characterization of the immune response and immune cells, including simultaneous detection of cell surface proteins, antigen specificity, as well as immune repertoire, gene expression, and chromatin profiling is now possible with single cell and multiomic approaches. Perform complex phenotyping in tens of thousands of immune cells by incorporating 10x Genomics technology into your existing flow cytometry workflow.
See how we recently demonstrated the immense scalability of our Feature Barcoding technology to produce a rich dataset elucidating the mechanisms of TCR-pMHC interactions.
Getting to the Next Level of Characterization & Resolution
Solutions from 10x Genomics enable immunology researchers to go beyond traditional cellular phenotyping approaches to get a more complete view of innate and adaptive immunity. See how researchers are incorporating 10x Genomics technology into their current workflows.
Learn More About Our Solutions to Explore the Immune System With Unprecedented Depth, Breadth, and Precision
The Chromium Single Cell Immune Profiling Solution allows you to simultaneously examine the cellular context of the adaptive immune response and immune repertoires of hundreds to tens of thousands of T and B cells in human or mouse on a cell-by-cell basis.Go to solution
The Chromium Single Cell ATAC Solution allows you to discover cellular heterogeneity stemming from epigenetic variability and better understand the regulation of genes to better define cell state and types for lineage tracing and biomarker discovery.Go to solution
The Chromium Single Cell Gene Expression Solution provides an unparalleled approach to uncover cell-to-cell gene expression variability and identify rare cell types from complex biological samples.Go to solution