Loupe V(D)J Browser is a desktop application for Windows and macOS that allows the user to analyze, search, and visualize V(D)J sequences and clonotypes from 5' Chromium Single Cell Immune Profiling
Loupe is named for a jeweler's loupe, which is used to inspect gems.
Using Loupe V(D)J Browser, you can quickly:
- Determine the most common paired alpha and beta TCR chains or heavy and light BCR chains in your sample
- Filter clonotypes based on their antigen specificity or UMI count per antigen
- Examine full-length V, D, and J amino acid and nucleotide sequences to detect variants within V(D)J transcripts
- Search for motifs within CDR3 regions
- Compare clonotype frequencies between samples
To find out how to use Loupe V(D)J Browser to explore your data, start the tutorial.