<LinkableSection id={"overview"} title={"Overview"}>

Sentira Single Cell runs on 10x Cloud Credits. 10x Cloud Credits are a single unit you use for everything you do in the application — running analyses, storing data, and downloading results.

</LinkableSection>

<LinkableSection id={"cloud-credits"} title={"10x Cloud Credits"}>

10x Cloud Credits are prepaid measures of entitlement to access and use certain 10x cloud-based software services. A 10x Cloud Credit is the unit you use across all paid activities in Sentira.

10x Cloud Credits are consumed by the following types of activity:

- **Compute**: Running an analysis workflow on a sample.
- **Storage**: All of the inputs and outputs in your Sentira Single Cell account consume 10x Cloud Credits per GB on a monthly basis.
- **Download (egress)**: Downloading your files from the 10x Cloud.

A positive 10x Cloud Credit balance is required to upload data or run analyses. If your balance reaches zero, you will not be able to upload new datasets, start new analysis workflows, or download files that consume 10x Cloud Credits until your balance is topped up with promotional or purchased 10x Cloud Credits. Many output files are small enough that their download consumes zero 10x Cloud Credits, so those will still be downloadable.

Storage continues to consume 10x Cloud Credits while your balance is zero or negative. Unpaid negative balances are handled as set out in the [10x Genomics Cloud Services Terms](https://www.10xgenomics.com/legal/cloud-terms-of-use).

You can find your 10x Cloud Credit consumption report under **Account** > **Settings** > **Billing and Usage** > **Credits**.

</LinkableSection>

<LinkableSection id={"promotional-credits"} title={"Promotional 10x Cloud Credits"}>

You do not need to purchase 10x Cloud Credits to get started. Each Sentira Single Cell account is currently eligible for a one-time grant of 100 10x Cloud Credits when you first upload data. These 10x Cloud Credits are not tied to any purchase, have no cash value, are non-transferable, expire as stated to the recipient at the time of grant, and may be revoked at 10x's discretion. When you upload a sample, you accept these grant conditions. This is a one-time grant per account. Subsequent uploads do not trigger additional grants. Promotional 10x Cloud Credit packs will be labeled in the billing section of your 10x Cloud account.

</LinkableSection>

<LinkableSection id={"action-costs"} title={"What each action consumes"}>

The table below shows the 10x Cloud Credits consumed by each paid action. The amounts shown below are estimates and the actual consumption depends on your usage. These 10x Cloud Credit amounts are current at the time of publication and are subject to change.

| Action                               | 10x Cloud Credits consumed                                                                | Notes                                                                                              |
| ------------------------------------ | ----------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------- |
| Single cell agentic analysis session | Variable based on analysis complexity and compute time. Estimated at ~12 credits/session. | Applies to agentic sessions. Credit consumption will vary based on the complexity of the analysis. |
| Data storage                         | 0.02 credits / GB / month                                                                 | Applies to uploaded data and analysis outputs in your 10x Cloud account.                           |
| Data download (egress)               | 0.10 credits / GB                                                                         | Downloading files to your computer. Consumed based on the volume actually downloaded.              |

</LinkableSection>

<LinkableSection id={"examples"} title={"What your 10x Cloud Credits cover"}>

Your actual 10x Cloud Credit usage will vary with the size of your experiments and complexity of your prompts.

For example, we estimate an average of 60 10x Cloud Credits consumed to analyze a multi-sample Chromium experiment of fewer than 500,000 cells, from upload to experimental conclusions. This estimate assumes five agentic analysis sessions, 12 months of storage, and two full output downloads. Real experimental usage will vary.

</LinkableSection>

<LinkableSection id={"buying-credits"} title={"Buying 10x Cloud Credits"}>

10x Cloud Credit packs can be purchased from the [10x Store](/store/product-catalog?product=10x-cloud). You will need a 10x Store account to log in.

Purchased 10x Cloud Credits expire 12 months after activation, are non-transferable, and are non-refundable.

Purchases are subject to the [10x Terms and Conditions of Sale](https://www.10xgenomics.com/legal/legal-notices).

</LinkableSection>

<LinkableSection id={"regional-availability"} title={"Regional availability"}>

10x Cloud Credits are available for purchase globally (except for excluded territories), subject to applicable trade control restrictions. You may inquire about access to Sentira in your region by reaching out to [10x Support](/support/contact). Use of Sentira is subject to the [10x Genomics Cloud Services Terms](https://www.10xgenomics.com/legal/cloud-terms-of-use).

</LinkableSection>


Overview

10x Cloud Credits

Promotional 10x Cloud Credits

What each action consumes

What your 10x Cloud Credits cover

Buying 10x Cloud Credits

Regional availability

Billing

An integrated, cloud-based platform for single cell and spatial analysis of Chromium, Xenium, and Atera data.

Sentira

Atera

Gene Expression

<LinkableSection id={"browser-support"} title={"Browser support"}>

We recommend accessing Sentira through a recent version of the web browsers listed below.

Supported desktop browsers:

- [Chrome](https://www.google.com/chrome)
- [Firefox](https://www.mozilla.org/firefox)
- [Edge](https://www.microsoft.com/edge)
- [Safari](https://www.apple.com/safari)

Supported tablet browsers:

- [Chrome](https://www.google.com/chrome)
- [Safari](https://www.apple.com/safari)

</LinkableSection>


Browser support

Browser Support

<LinkableSection id={"sentira-sc"} title={"Sentira Single Cell Analysis"}>

Sentira Single Cell supports downstream analysis of data from the Chromium single cell products listed below.

| **Chromium Product** | **Library Types**                                                                                                                                                                                                                                                                              | **10x Pipeline** |
| -------------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ---------------- |
| Universal 3'         | <ul><li>Universal 3' Gene Expression</li><li>Feature Barcode<ul><li>Antibody Capture</li><li>CRISPR Guide Capture</li><li>Custom Library</li></ul></li><li>Sample multiplexing<ul><li>3' CellPlex</li><li>On-chip multiplexing (OCM)</li><li>Hashing with Antibody Capture</li></ul></li></ul> | Cell Ranger      |
| Universal 5'         | <ul><li>Universal 5' Gene Expression</li><li>Universal 5' V(D)J</li><li>Feature Barcode<ul><li>Antibody Capture</li><li>CRISPR Guide Capture</li></ul></li><li>Sample multiplexing<ul><li>Hashing with Antibody Capture</li></ul></li></ul>                                                    | Cell Ranger      |
| Flex                 | <ul><li>Flex Gene Expression</li><li>Feature Barcode<li>Flex Antibody Capture</li><li>Flex CRISPR Guide Capture</li></li></ul>                                                                                                                                                                 | Cell Ranger      |
| Epi ATAC             | <ul><li>ATAC</li></ul>                                                                                                                                                                                                                                                                         | Cell Ranger ATAC |
| Epi Multiome         | <ul><li>Epi Multiome ATAC + Gene Expression</li></ul>                                                                                                                                                                                                                                          | Cell Ranger ARC  |

</LinkableSection>


Sentira Single Cell Analysis

Supported Products

Sentira is an integrated, cloud-based platform for single cell and spatial analysis of 10x Genomics data. It brings analysis, iteration, and collaboration together in a single connected experience, reimagining how researchers work with 10x data.

Getting Started

Tutorials

Release Notes

Analysis Guides

Learn how to set up a 10x Cloud account to use Sentira.

Introduction

Account Creation

Learn about the Sentira interface and features.

Interface and Features

Sentira Single Cell Tutorial

What is Sentira?

Browse Q&As from the 10x Genomics support team.

A collection of introductions, tutorials, and blogs for data analysis beyond 10x Genomics software.

Miscellaneous