Protein subpanels
Same cell gene and protein expression
Multiplex up to 27 proteins with 100’s of RNA targets
Why choose protein subpanels
Ready-to-use, pre-optimized, and validated subpanels
Multiomic spatial characterization of the immune and tumor microenvironment
Assay specifications
Human
Species
FFPE tissue
Compatible samples
Compatible gene panels
Ready-to-use human panels Add on up to 100 custom genes
Custom human <500-gene panels
Probe-based gene expression
Protein (Xenium subpanels)
Morphology (H&E)
Protein (IF) Post-Xenium run
Same section capabilities
Compatible instruments
Throughput options
2 Xenium slides per run (up to 472 mm² of tissue) ~ 5 days per run
Ready-to-use subpanel options
Immune Cell Subpanel A
CD3
CD4
CD8
CD20
Immune Cell Subpanel B
HLA-DR
CD68
CD11c
CD138
Immune Cell Subpanel C
Granzyme B
CD163
CD16
Tumor Subpanel
PanCK
CD31
Beta-catenin
PTEN
Proliferation & Differentiation Subpanel
CD45RA
CD45RO
PCNA
Ki-67
Immune Checkpoint Subpanel
PD-1
PD-L1
VISTA
LAG3
Find a Xenium panel
The Xenium Panel Selector helps you find the right panel, letting you filter by and/or enter genes to check overlap with 10x Genomics pre-designed panels. It also highlights genes for custom add-on panels.
Assay components
Consumables
Xenium Protein
1000885
Xenium RNA & Protein Assay Bundle (2 rxns)
1000837
Xenium Protein Tumor Subpanel (2rxns)
1000836
Xenium Protein Immune Checkpoint Subpanel (2rxns)
1000835
Xenium Protein Proliferation & Differentiation Subpanel (2rxns)
1000846
Xenium Protein Immune Cell Subpanel C (2rxns)
1000834
Xenium Protein Immune Cell Subpanel B (2rxns)
1000833
Xenium Protein Immune Cell Subpanel A (2rxns)
Documents and resources
Resources
Advancing tumor characterization and immune phenotyping through multiomic in situ profiling of RNA and proteins
Xenium In Situ Gene and Protein Expression data for FFPE Human Renal Cell Carcinoma
How TGen drastically reduced Xenium per-sample costs for large cohorts with tumor microarrays
Data analysis
Xenium Onboard Analysis
The Xenium platform processes data in parallel with imaging and biochemistry cycles, allowing immediate access to interpretation-ready data without time-consuming steps post-run.
Xenium Ranger
With compatibility across multiple Linux distributions, the Xenium Ranger analysis pipelines make it easy to reanalyze your Onboard Analysis data and visualize it in Xenium Explorer.
Xenium Explorer
Xenium Explorer is a desktop application for Windows and MacOS that allows you to interactively visualize data generated by the Xenium Analyzer instrument.
Featured datasets
Related products
Xenium <500-gene panels
Ready-to-use and custom panels deliver mid-plex targeted gene expression and optional in-line protein expression for focused single cell spatial discovery.
Flex
Fixed RNA Profiling assay for comprehensive probe-based gene expression profiling with single cell resolution.
Visium HD 3'
Species agnostic 3' poly(A) capture-based spatial gene expression assay for expanded whole transcriptome discovery applications.