Xenium In Situ
<500-gene panels
Xenium RNA v1 chemistry–powered panels deliver mid-plex targeted gene expression for focused single cell spatial discovery.
Highest sensitivity for focused tissue & pathway characterization
Design fully custom panels up to 480 genes
Why choose <500-gene panels
Assay specifications
Species
Mouse
Human
Additional species with custom panelsCompatible samples
FFPE tissue
Fresh frozen tissue
Tumor microarrays (TMAs)Same section capabilities
Customization
Xenium Custom Panel DesignerDesign fully custom panels up to 480 genes or add on up to 100 custom genes to pre-designed panelsCompatible instruments
Throughput options
~3 days per run
Ready-to-use panel options
Characterize human and mouse tissues and pathways with focused 250–380 gene panels.
Human Immuno-Oncology
Includes gene markers for major immune cell types, checkpoint markers, etc.
Human Multi-Tissue and Cancer
Includes gene markers for breast, colon, heart, kidney, liver, lung, pancreas, etc.
Human Breast
Breast glandular cells, epithelial cells, adipocytes, tumor, etc.
Mouse Brain
Astrocytes, interneurons, microglia oligodendrocytes, etc.
Human Brain
Astrocytes, microglia, glioblastoma, Alzheimer's disease, Parkinson's disease, etc.
Human Lung
Alveolar type 1 & 2, ciliated cells, endothelial cells, COVID-19, etc.
Mouse Tissue Atlassing
Includes gene markers for bladder, bone marrow, brain, heart, kidney, limb muscle, lung, pancreas, thymus, etc.
Human Skin
Keratinocytes, melanocytes, vascular endothelial, immune cells, melanoma, etc.
Human Colon
Absorptive enterocytes, enteroendocrine cells, goblet cells, paneth cells, fibroblasts, etc.
Find a Xenium panel
The Xenium Panel Selector helps you find the right panel, letting you filter by and/or enter genes to check overlap with 10x Genomics pre-designed panels. It also highlights genes for custom add-on panels.
Assay components
Each experiment requires Xenium slides, core reagents, and the Xenium Analyzer instrument. If you're unsure what you need, use the experiment builder to compile a custom list of items required for your experiment.
Consumables
Instrument Consumables
1000487
Xenium Decoding Consumables (1 run, 2 slides)
1000461
Xenium Decoding Reagents (1 run, 2 slides)
1000566
Xenium Cassettes (2 cassettes)
Assay Consumables
1000460
Xenium Slides & Sample Prep Reagents (2 slides, 2 rxns)
1000662
Xenium Cell Segmentation Add-on Kit (2 rxns)
Xenium Protein
1000885
Xenium RNA & Protein Assay Bundle (2 rxns)
1000837
Xenium Protein Tumor Subpanel (2rxns)
1000836
Xenium Protein Immune Checkpoint Subpanel (2rxns)
1000835
Xenium Protein Proliferation & Differentiation Subpanel (2rxns)
1000846
Xenium Protein Immune Cell Subpanel C (2rxns)
1000834
Xenium Protein Immune Cell Subpanel B (2rxns)
1000833
Xenium Protein Immune Cell Subpanel A (2rxns)
Predesigned Panels
1000462
Xenium Mouse Brain Gene Expression Panel (2 rxns)
1000463
Xenium Human Breast Gene Expression Panel (2 rxns)
1000599
Xenium Human Brain Gene Expression Panel (2 rxns)
1000601
Xenium Human Lung Gene Expression Panel (2 rxns)
1000626
Xenium Human Multi-Tissue and Cancer Panel (2 rxns)
1000627
Xenium Mouse Multi-Tissue Atlassing Panel (2 rxns)
1000642
Xenium Human Colon Gene Expression Panel Kit (2 rxns)
1000643
Xenium Human Skin Gene Expression Panel Kit (2 rxns)
1000654
Xenium Human Immuno-Oncology Profiling Panel (2 rxns)
Add-On Custom Panel (requires Predesigned Panel for Design)
1000652
Xenium Add-on Custom 1 to 50 Gene Panel (4 rxns)
1000464
Xenium Add-on Custom 1 to 50 Gene Panel (16 rxns)
1000651
Xenium Add-on Custom 51 to 100 Gene Panel (4 rxns)
1000561
Xenium Add-on Custom 51 to 100 Gene Panel (16 rxns)
Standalone Custom Panel
1000650
Xenium Standalone Custom 1 to 50 Gene Panel (4 rxns)
1000646
Xenium Standalone Custom 1 to 50 Gene Panel (16 rxns)
1000649
Xenium Standalone Custom 51 to 100 Gene Panel (4 rxns)
1000645
Xenium Standalone Custom 51 to 100 Gene Panel (16 rxns)
1000648
Xenium Standalone Custom 101 to 300 Gene Panel (4 rxns)
1000563
Xenium Standalone Custom 101 to 300 Gene Panel (16 rxns)
1000647
Xenium Standalone Custom 301 to 480 Gene Panel (4 rxns)
1000644
Xenium Standalone Custom 301 to 480 Gene Panel (16 rxns)
Accessory
1000623
Xenium Thermocycler Adaptor Kit
Training
1000632
Xenium Analyzer Premium 3-Day Training Visit
Documents and resources
Resources
Advancing tumor characterization and immune phenotyping with multiomic in situ profiling of RNA and proteins
Download poster
Molecular dissection of the tumor microenvironment using the Xenium Human Immuno-Oncology Panel
Download the application note
High-throughput projection tracing and multi-modal mapping of the mouse brain
Watch on-demand webinarData analysis
Xenium Onboard Analysis
The Xenium platform processes data in parallel with imaging and biochemistry cycles, allowing immediate access to interpretation-ready data without time-consuming steps post-run.
Learn about Onboard Analysis
Xenium Ranger
With compatibility across multiple Linux distributions, the Xenium Ranger analysis pipelines make it easy to reanalyze your Onboard Analysis data and visualize it in Xenium Explorer.
Learn about Xenium Ranger
Xenium Explorer
Xenium Explorer is a desktop application for Windows and MacOS that allows you to interactively visualize data generated by the Xenium Analyzer instrument.
Download Xenium ExplorerFeatured datasets
Xenium In Situ Gene and Protein Expression data for FFPE Human Renal Cell Carcinoma
View datasetFFPE Human Lung Cancer Data with Human Immuno-Oncology Profiling Panel and Custom Add-on
View datasetFresh Frozen Mouse Colon with Mouse Tissue Atlassing Panel and Xenium Multimodal Cell Segmentation
View datasetRelated products
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