<500-gene panels
Highest sensitivity for focused tissue & pathway characterization
Design fully custom panels up to 480 genes
Why choose <500-gene panels
Broad species compatibility enabled by custom panels
Same-section multiomics using the Xenium Protein subpanels
Largest menu of pre-designed, customizable panels for human and mouse
Assay specifications
Mouse
Human
Additional species with custom panels
Species
FFPE tissue
Fresh frozen tissue
Tumor microarrays (TMAs)
Compatible samples
Same section capabilities
Customization
Design fully custom panels up to 480 genes or add on up to 100 custom genes to pre-designed panels
Compatible instruments
Throughput options
2 Xenium slides per run (up to 472 mm² of tissue) ~3 days per run
Ready-to-use panel options
Human Immuno-Oncology
Includes gene markers for major immune cell types, checkpoint markers, etc.
380 genes on panel
Up to 100 add-on genes
Human Multi-Tissue and Cancer
Includes gene markers for breast, colon, heart, kidney, liver, lung, pancreas, etc.
377 genes on panel
Up to 100 add-on genes
Human Breast
Breast glandular cells, epithelial cells, adipocytes, tumor, etc.
280 genes on panel
Up to 100 add-on genes
Human Brain
Astrocytes, microglia, glioblastoma, Alzheimer's disease, Parkinson's disease, etc.
266 genes on panel
Up to 100 add-on genes
Human Lung
Alveolar type 1 & 2, ciliated cells, endothelial cells, COVID-19, etc.
289 genes on panel
Up to 100 add-on genes
Human Skin
Keratinocytes, melanocytes, vascular endothelial, immune cells, melanoma, etc.
260 genes on panel
Up to 100 add-on genes
Human Colon
Absorptive enterocytes, enteroendocrine cells, goblet cells, paneth cells, fibroblasts, etc.
322 genes on panel
Up to 100 add-on genes
Mouse Brain
Astrocytes, interneurons, microglia oligodendrocytes, etc.
247 genes on panel
Up to 100 add-on genes
Mouse Tissue Atlassing
Includes gene markers for bladder, bone marrow, brain, heart, kidney, limb muscle, lung, pancreas, thymus, etc.
379 genes on panel
Up to 100 add-on genes
Find a Xenium panel
The Xenium Panel Selector helps you find the right panel, letting you filter by and/or enter genes to check overlap with 10x Genomics pre-designed panels. It also highlights genes for custom add-on panels.
Assay components
In Situ Gene Expression
To order a custom panel with your preferred gene list, please use the Xenium Panel Designer to select your gene list and generate a Custom Design Panel (CDP) number. For more complex projects, please contact your Account Executive and ask about Advanced Custom panels.
Documents and resources
User guides
Sample prep
Customization
Technical notes
Analysis guides
Resources
Advancing tumor characterization and immune phenotyping with multiomic in situ profiling of RNA and proteins
Molecular dissection of the tumor microenvironment using the Xenium Human Immuno-Oncology Panel
High-throughput projection tracing and multi-modal mapping of the mouse brain
Data analysis
Xenium Onboard Analysis
The Xenium platform processes data in parallel with imaging and biochemistry cycles, allowing immediate access to interpretation-ready data without time-consuming steps post-run.
Xenium Ranger
With compatibility across multiple Linux distributions, the Xenium Ranger analysis pipelines make it easy to reanalyze your Onboard Analysis data and visualize it in Xenium Explorer.
Xenium Explorer
Xenium Explorer is a desktop application for Windows and MacOS that allows you to interactively visualize data generated by the Xenium Analyzer instrument.
Featured datasets
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