* Supports reanalysis of Xenium Onboard Analysis data up to version 1.7 (see [version compatibility table](/support/software/xenium-ranger/getting-started/XR-getting-started-with-xenium-ranger#compatibility)).
* The image-based `import-segmentation --coordinate-transform` [option](/support/software/xenium-ranger/analysis/running-pipelines/XR-import-segmentation#xr-matrix) is now compatible with segmentation masks (previously limited to polygons).
* Improved memory usage in the `import-segmentation` pipeline (see updated [system requirements page](/support/software/xenium-ranger/downloads/XR-system-requirements)).
* Fixed bug where input masks with discontinuous cells or nuclei caused Xenium Ranger to occasionally crash. An analysis summary alert was introduced to flag rare scenarios where discontinuities may lead to splitting of imported cells or nuclei.
* Several minor bug fixes in the analysis summary user interface.
* Improved preflight checks.
* Miscellaneous bug fixes.

v1.7 (October 9, 2023)

* Initial release.
* Resegment Xenium data with customizable nucleus expansion distance and the latest 10x cell segmentation algorithm.
* Import community-developed nucleus and cell segmentations in multiple popular formats (i.e., Baysor).
* Selected the wrong gene panel when you started the Xenium Analyzer run? Simply fix the mistake by using relabel.
* All pipelines produce the same output bundle as Xenium Onboard Analysis v1.6, so they are compatible with the same downstream visualization and analysis softwares (e.g., Xenium Explorer).
* Backwards compatible with all previous Xenium Onboard Analysis versions.

v1.6 (August 17, 2023)

Release Notes for Xenium Ranger

Overview

Getting Started

Download Center

Xenium Ranger Commands

Analysis

Algorithms

Advanced

Release Notes

Xenium Onboard Analysis

Xenium Explorer

Datasets

Analysis Guides

Xenium Ranger

Learn more about input files required for Xenium Ranger

Inputs

Learn how to run Xenium Ranger subcommands.

Running Pipelines

Guidance for choosing a Xenium Ranger pipeline.

Choosing a Pipeline

Relabel

Modify the Xenium Onboard Analysis cell segmentation results.

Resegment

Import segmentation results from community-developed tools.

Import-segmentation

Learn more about output files generated by Xenium Ranger

Outputs

The Xenium In Situ software suite is a set of software applications for analyzing and visualizing in situ gene expression data produced by the Xenium Analyzer. Xenium Ranger provides flexible off-instrument reanalysis of Xenium In Situ data. Relabel transcripts, resegment cells with the latest 10x segmentation algorithms, or import your own segmentation data to assign transcripts to cells.

What is Xenium Ranger?

Learn about Xenium Ranger, software compatibility, and analysis workflows.

Getting Started with Xenium Ranger

New to Xenium Ranger?

We provide resources from protocols, user guides, and free-to-use analysis tools.

View the latest updates to Xenium Ranger algorithms.

View the latest updates to Xenium Ranger.

Learn more about Xenium In Situ instrument analysis software.

Visualize data from Xenium In Situ solutions.

Browse Q&As from the 10x Genomics support team.

Access free, publicly available data generated with Xenium In Situ solutions.

A collection of introductions, tutorials, and blogs for data analysis beyond 10x Genomics software.