Xenium In Situ
Protein subpanels
Combine pre-optimized protein subpanels with Xenium <500-gene panels for enhanced multiomic biomarker analyses.
Same cell gene and protein expression
Multiplex up to 27 proteins with 100’s of RNA targets
Why choose protein subpanels
Assay specifications
Species
HumanCompatible samples
FFPE tissueCompatible gene panels
Same section capabilities
Probe-based gene expression
Protein (Xenium subpanels)
Morphology (H&E)
Protein (IF)Post-Xenium runCompatible instruments
Throughput
~ 5 days per run
Ready-to-use subpanel options
Xenium Protein subpanels are purchased separately. Multiplex all 6 subpanels or only run subpanels of interest. Cell segmentation markers (E-cadherin, Vimentin, AlphaSMA, and CD45) are required for Xenium Protein runs and are included in the Xenium RNA & Protein Assay Bundle.
Find a Xenium panel
The Xenium Panel Selector helps you find the right panel, letting you filter by and/or enter genes to check overlap with 10x Genomics pre-designed panels. It also highlights genes for custom add-on panels.
Assay components
Each experiment requires Xenium slides, core reagents, and the Xenium Analyzer instrument. If you're unsure what you need, use the experiment builder to compile a custom list of items required for your experiment.
Consumables
Xenium Protein
1000885
Xenium RNA & Protein Assay Bundle (2 rxns)
1000837
Xenium Protein Tumor Subpanel (2rxns)
1000836
Xenium Protein Immune Checkpoint Subpanel (2rxns)
1000835
Xenium Protein Proliferation & Differentiation Subpanel (2rxns)
1000846
Xenium Protein Immune Cell Subpanel C (2rxns)
1000834
Xenium Protein Immune Cell Subpanel B (2rxns)
1000833
Xenium Protein Immune Cell Subpanel A (2rxns)
Documents and resources
Resources
Advancing tumor characterization and immune phenotyping through multiomic in situ profiling of RNA and proteins
Download poster
Xenium In Situ Gene and Protein Expression data for FFPE Human Renal Cell Carcinomal
Explore interactive data demo
How TGen drastically reduced Xenium per-sample costs for large cohorts with tumor microarrays
Read the blogData Analysis
Xenium Onboard Analysis
The Xenium platform processes data in parallel with imaging and biochemistry cycles, allowing immediate access to interpretation-ready data without time-consuming steps post-run.
Learn about Onboard Analysis
Xenium Ranger
With compatibility across multiple Linux distributions, the Xenium Ranger analysis pipelines make it easy to reanalyze your Onboard Analysis data and visualize it in Xenium Explorer.
Learn about Xenium Ranger
Xenium Explorer
Xenium Explorer is a desktop application for Windows and MacOS that allows you to interactively visualize data generated by the Xenium Analyzer instrument.
Download Xenium ExplorerFeatured datasets
Xenium In Situ Gene and Protein Expression data for FFPE Human Renal Cell Carcinoma
View datasetRelated products
Xenium <500-gene panels
Ready-to-use and custom panels deliver mid-plex targeted gene expression and optional in-line protein expression for focused single cell spatial discovery.
Flex Gene Expression
Fixed RNA Profiling assay for comprehensive probe-based gene expression profiling with single cell resolution.
Visium HD 3’
Species agnostic 3’ poly(A) capture-based spatial gene expression assay for expanded whole transcriptome discovery applications.