Read our Single Cell CNV product update

Genomics at
Single Cell Resolution

Chromium Single Cell CNV Solution

Copy Number Profiling at Single Cell Resolution

The Chromium Single Cell CNV Solution provides a comprehensive, scalable solution for revealing genome heterogeneity and understanding clonal evolution. Study disease pathogenesis or characterize neuronal mosaicism at the single cell level.

Our Solution Features

  • Profiles 100s to 1000s of cells
  • Accurately calls single cell CNV events at 2 Mb resolution
  • Detects CNV events down to 100s of Kb on clusters of cells
  • Demonstrated with cell lines, primary cells, fresh and frozen tissue
  • Push-button analysis and visualization software
View the Workflow
Single Cell CNV Product Suite
 

Watch: How It Works

Analyze Genomes, Cell by Cell

Learn more about how to determine genomic heterogeneity and map clonal evolution by profiling hundreds to thousands of cells in a single sample.

Chromium Controller

Compact, Sleek, Efficient.

The compact, sleek Chromium Controller rapidly and efficiently combines large partition numbers with a massively diverse barcode library to generate >100,000 barcode-containing partitions in a matter of minutes. The Chromium Controller fits on a standard laboratory bench and allows a user to run any Chromium Solution, from genome to single cell analysis.

View Our Controller Gallery
Single Cell DNA Controller

Product List

Chromium Single Cell CNV Solution

Available for use only with the Chromium Controller (Part Numbers 120223 and 120246) or the Chromium Single Cell Controller (Part Numbers 120263 and 120212).

Product Update

Chip kits for the Chromium Single Cell CNV Solution (Product Codes 1000032, 1000036, 1000022, and 1000022) are no longer available as of February 2020. If you are an existing CNV customer in the United States, please contact your Sales Executive or email our Support Team at support@10xgenomics.com.

Reagents & Consumables

Reactions
Product Code
Chromium Chip C Single Cell DNA Kit
1000032
1000022
Chromium Chip D Single Cell DNA Kit
1000036
1000042
Chromium i7 Multiplex Kit
96 rxns
120262
Chromium Single Cell DNA Cell Bead Kit
1000057
1000056
Chromium Single Cell DNA Library and Gel Bead Kit
1000041
1000040
Flowmi Filter
50 rxns
1000055

Instrument Accessories

Product Code
10x Chromium Chip D Holder
1000053
10x Magnetic Separator A
1000054

Software

Cell Ranger DNA Analysis Pipelines
Loupe scDNA Browser
Single Cell CNV Datasets
Scientific Seminars

Leveraging Single Cell Copy Number to Resolve Tumor Clonality

 
  • Dr. David W. Craig, Professor of Translational Genomics; Co-Director, Institute of Translational Genomics Keck School of Medicine of USC
Professor of Translational Genomics; Co-Director, Institute of Translational Genomics Keck School of Medicine of USC
November 12, 2019

CHISELing out Allele- and Haplotype-specific Copy Numbers in Single Cells

 
  • Ben Raphael, PhD, Professor of Computer Science, Princeton University
Professor of Computer Science, Princeton University
October 15, 2019

Sample Preparation for Single Cell Analysis: Tips and Tricks

 
  • Jill Herschleb, PhD, Director, Sample Preparation, 10x Genomics
Director, Sample Preparation, 10x Genomics
August 14, 2019

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