Xenium Spatial Platform

Unparalleled single cell spatial discovery

Characterize 100s to 1,000s of RNAs in cells and tissues with subcellular in situ resolution.

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Xenium breast cancer sample data

The ultimate single cell spatial biology experience

The Xenium platform delivers high-plex in situ at subcellular resolution with nanometer precision and offers a complete solution, including comprehensive panel offerings, to achieve fast and robust single cell spatial insights.

10x Genomics Xenium platform

Gene and protein panels

Customizable ready-to-use panels or fully custom gene panels with add-on protein subpanels

Xenium Analyzer instrument

Industry-leading speed and throughput for single cell spatial imaging

Data analysis

Powerful on-board analysis and Xenium Explorer visualization software

Xenium Protein

Pre-order now: Xenium Protein

Integrated protein & RNA for deeper insights

  • Enhance immune and tumor microenvironment analyses with 27 immune, cancer & proliferation markers
  • Streamline RNA & protein profiling with a single integrated workflow
  • No protein expertise needed with easy-to-use, pre-optimized & validated protein subpanels
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Built for rapid data exploration

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Immediate data access

Access your data as soon as the Xenium run is complete.

10x Genomics Xenium analyzer touchscreen

Easy-to-use interface

Intuitively visualize morphology, protein markers, segmentation, cell typing, and transcript density—no bioinformatics experience required.

10x Genomics Xenium analyzer touchscreen

Explore at any scale

Seamlessly explore your data at any scale, from whole tissue sections to single transcripts.

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A state-of-the-art single cell spatial imaging instrument

  • Seamlessly integrates transcript detection workflow, high-resolution imaging, decoding, and onboard data analysis for fresh frozen or FFPE tissues
  • Simple run setup and cleanup operations, an intuitive touchscreen, and ergonomic design make instrument operation a breeze
  • Go from tissue section to data for up to 5,000 genes in ≤6 days or get even faster analysis times with smaller gene panels
10x Genomics Xenium Analyzer being used by a scientist in the lab
10x Genomics Xenium Analyzer with the door open showing reagents

Diverse panel menu to fit any research need

  • Comprehensive off-the-shelf menu of 10+ pre-designed gene panels, ranging from 50 to 5,000 genes
  • Build fully custom panels of up to 480 genes or add up to 100 genes to a pre-designed panel with our Custom Panel Designer
  • Add T- and B-cell receptors, SNVs, and isoforms with advanced custom design services
  • NEW! Add-on Xenium Protein subpanels for deeper characterization of the immune and tumor microenvironment
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Xenium Catalyst Program

Discover the power of Xenium technology with our in-house pilot run service

Our Catalyst program lets you test drive the Xenium platform, evaluate its capabilities, and explore your spatial transcriptomics data alongside a team of scientific experts.

End-to-end service completed in as few as

4 weeks

Complete access to fully custom or

10+ panels

10x Genomics Xenium platform

Resources

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See Xenium Protein data in action

Get a hands-on look at what same-section protein and high-plex spatial RNA can show you in this interactive Xenium web demo.

Explore interactive dataset
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Get to know the Xenium platform

Explore the unique platform features, from padlock chemistry to panels, that power the ultimate single cell spatial biology experience.

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Grant writing assistance

Get the information you need to write grants featuring Xenium experiments (including technology overview, benchmarking data, and more).

See what Xenium users are saying

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Unlock the full spectrum of biology

Build on your Xenium Spatial insights with comprehensive, whole transcriptome single cell and spatial analysis.

Platform

Chromium Single Cell platform

Chromium Single Cell platform

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Xenium Spatial platform

Xenium Spatial platform

Visium Spatial platform

Visium Spatial platform

When to use

Comprehensive single cell data

Ideal for deep characterization of cell populations and states.

High-resolution discovery

Understand complex tissues, neighborhoods, and cell to cell interactions. Integration with other spatial-omics, histology, and morphology. 

Why use

Unbiased single cell discovery

High per-gene sensitivity

Single cell spatial discovery

High per-gene sensitivity

Expanded spatial discovery

Applications

Whole transcriptome gene expression

Protein

TCR, BCR

CRISPR

ATAC

Targeted gene expression (up to 5,000 genes)

Multiomic gene and protein expression (up to 480 genes and 27 proteins)

Whole transcriptome gene expression

Resolution

Single cell

Subcellular

Single cell–scale

Data readout

NGS-based

Imaging-based

NGS-based

Sample compatibility

Single cell or nuclei suspensions from fresh, frozen, or FFPE samples

Fresh frozen

FFPE

FFPE

Fresh frozen

Fixed frozen

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Xenium Spatial platform

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