Chromatin Accessibility at Single Cell Resolution

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The Chromium Single Cell ATAC (Assay for
Transposase Accessible Chromatin) Solution

Reveal chromatin accessibility cell by cell with single cell epigenomics

The Chromium Single Cell ATAC (Assay for Transposase Accessible Chromatin) Solution accelerates the understanding of the regulatory landscape of the genome, thereby providing insights into cell variability. The chromatin profiling of tens of thousands of single cells in parallel allows researchers to see how chromatin compaction and DNA-binding proteins regulate gene expression at high resolution.

The Chromium Single Cell ATAC Solution also includes intuitive software analysis and visualization tools for a refined analysis of gene regulatory networks in single cells. The Chromium Single Cell ATAC Solution can be used to study developmental plasticity, cellular heterogeneity, and beyond.

  • Discover cellular heterogeneity stemming from epigenetic variability
  • Better understand the gene regulatory networks that are upstream of gene expression
  • Define cell types and states for lineage and developmental program tracing
  • Accelerate biomarker discovery

Our Solution Features

  • Detect open chromatin regions in single cells with enriched signals in Transcription Start Sites (TSS) and regulatory regions
  • Profile 500 to 10,000 nuclei per channel with our scalable, high-throughput solution
  • Recover up to 65% of nuclei loaded on chips
  • Investigate cell lines, primary cells, fresh, and cryopreserved samples with confidence
  • Analyze your single cell epigenetic data with our turnkey analysis software and interactive visualization tools
  • Available with Next GEM technology
View the Workflow
Single Cell ATAC Solution

Single Cell ATAC-seq

Watch how it works

Obtain genome-wide chromatin accessibility information by analyzing tens of thousands of nuclei in parallel. Identify open chromatin regions by using a transposase enzyme to preferentially insert and tag accessible DNA fragments with adaptors, to get sequencing ready libraries in a day. Following sequencing, analyze and visualize your high resolution epigenetic data with our easy to use software.

The Chromium Controller

Compact, Sleek, Efficient.

The compact, sleek Chromium Controller rapidly and efficiently combines large partition numbers with a massively diverse barcode library to generate >100,000 barcode-containing partitions in a matter of minutes. The Chromium Controller fits on a standard laboratory bench and allows a user to run any Chromium Solution, from genome to single cell analysis.

View Our Controller Gallery
Single Cell Controller

Product List

Chromium Single Cell ATAC Solution

Single Cell ATAC Version

Reagents & Consumables

Reactions
Product Code
Chromium Chip E Single Cell ATAC Kit
1000086
1000082
Chromium i7 Multiplex Kit N, Set A
96 rxns
1000084
Chromium Next GEM Chip H Single Cell Kit
1000162
1000161
Chromium Next GEM Single Cell ATAC Library & Gel Bead Kit v1.1
1000176
1000175
Chromium Single Cell ATAC Library & Gel Bead Kit
1000111
1000110

Instruments

Warranty
Product Code
Chromium Controller & Next GEM Accessory Kit
120223
120246

Software

Cell Ranger ATAC
Loupe Cell Browser

Documentation

Chromium Single Cell ATAC Reagent Kits User Guide (v1.1 Chemistry)

*Multiplex Kit that is compatible with the Chromium Single Cell ATAC Solution

Single Cell ATAC Datasets
Scientific Seminars

单细胞ATAC-Seq入门:高分辨率表观基因组学研究

 
  • Sophie Zhao (赵琳琳)
Regional Marketing Manager, China, 10x Genomics
April 24, 2019

Getting Started with Single Cell ATAC Sequencing for High Resolution Epigenomic Studies

 
  • Laura DeMare, Ph.D.
Associate Product Manager, Epigenomics, 10x Genomics
April 23, 2019

シングルセルATAC-Seqを始めよう:高解像度のエピゲノム解析

 
  • 大崎 研
Regional Marketing Manager, 10x Genomics
April 22, 2019
Poster Hall

High throughput immune profiling using integrated single cell multi-omics analyses

  • Single Cell Biology Keystone Symposia
    Breckenridge, CO
    January 2019

Single cell ATAC-seq for characterization of complex biological systems

  • Human Cell Atlas Conference
    Cambridge, MA
    November 2018

Single cell ATAC-seq for characterization of complex biological systems

  • Single Cell Biology Keystone Symposia
    Breckenridge, CO
    January 2019

Order your 10x system, today.

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