Chromatin Accessibility at Single Cell Resolution

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The Chromium Single Cell ATAC (Assay for
Transposase Accessible Chromatin) Solution

Reveal chromatin accessibility cell by cell with single cell epigenomics

The Chromium Single Cell ATAC (Assay for Transposase Accessible Chromatin) Solution accelerates the understanding of the regulatory landscape of the genome, thereby providing insights into cell variability. The chromatin profiling of tens of thousands of single cells in parallel allows researchers to see how chromatin compaction and DNA-binding proteins regulate gene expression at high resolution.

The Chromium Single Cell ATAC Solution also includes intuitive software analysis and visualization tools for a refined analysis of gene regulatory networks in single cells. The Chromium Single Cell ATAC Solution can be used to study developmental plasticity, cellular heterogeneity, and beyond.

  • Discover cellular heterogeneity stemming from epigenetic variability
  • Better understand the gene regulatory networks that are upstream of gene expression
  • Define cell types and states for lineage and developmental program tracing
  • Accelerate biomarker discovery

Our Solution Features

  • Detect open chromatin regions in single cells with enriched signals in Transcription Start Sites (TSS) and regulatory regions
  • Profile 500 to 10,000 nuclei per channel with our scalable, high-throughput solution
  • Recover up to 65% of nuclei loaded on chips
  • Investigate cell lines, primary cells, fresh, and cryopreserved samples with confidence
  • Analyze your single cell epigenetic data with our turnkey analysis software and interactive visualization tools
View the Workflow
Single Cell ATAC Solution

Single Cell ATAC-seq

Watch how it works

Obtain genome-wide chromatin accessibility information by analyzing tens of thousands of nuclei in parallel. Identify open chromatin regions by using a transposase enzyme to preferentially insert and tag accessible DNA fragments with adaptors, to get sequencing ready libraries in a day. Following sequencing, analyze and visualize your high resolution epigenetic data with our easy to use software.

The Chromium Controller

Compact, Sleek, Efficient.

The compact, sleek Chromium Controller has been designed to rapidly and efficiently automate the equivalent of 100,000s to 1,000,000s of pipetting steps for highly parallel sample partitioning and molecular barcoding. The Chromium Controller allows a user to run any Chromium Solution, spanning from genome to single cell analysis. A dedicated Chromium Single Cell Controller is also available for users who exclusively run Single Cell Solutions.

View Our Controller Gallery Download Technology Brochure (ATAC)
Single Cell Controller

Product List

Chromium Single Cell ATAC Solution

Product Name Product Code
Chromium Single Cell ATAC Library & Gel Bead Kit, 16 rxns 1000110
Chromium Single Cell ATAC Library & Gel Bead Kit, 4 rxns 1000111
Chromium Single Cell ATAC Chip E Kit, 48 rxn 1000082
Chromium Single Cell ATAC Chip E Kit, 16 rxn 1000086
Chromium i7 Multiplex Kit N, Set A, 96 rxn* 1000084
Chromium Single Cell Controller & Accessory Kit, 12 Mo. Warranty 120263
Chromium Single Cell Controller & Accessory Kit, 24 Mo. Warranty 120212
Chromium Controller & Accessory Kit, 24 Mo. Warranty 120246
Chromium Controller & Accessory Kit, 12 Mo. Warranty 120223
Cell Ranger ATAC Coming soon
Loupe Cell Browser Coming soon

*Multiplex Kit that is compatible with the Chromium Single Cell ATAC Solution

Single Cell ATAC Software

Software

Single Cell ATAC Datasets
Application Notes

Order your Chromium Single Cell Controller, today.

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