Chromium Single Cell

Epi Multiome ATAC + Gene Expression

Single cell profiling of open chromatin and 3' gene expression from the same nucleus

10K nuclei/sample or 80K nuclei/chip

Run 8 samples in parallel

NEW! GEM-X Epi Multiome

  • Count on robust results for same-cell open chromatin and gene expression profiles

  • Access deeper insights with higher sensitivity and profiling of up to 20K nuclei per sample

  • Achieve up to 80% nuclei recovery with advanced GEM-X microfluidics

Assay specifications

    Species

  • Mouse

  • Human

  • Rat

  • Non-human primate

  • Marine

  • Plant

  • Insect

    Compatible samples

  • Cell suspension

  • Nuclei suspension

  • Fresh tissue

  • Frozen tissue

  • Organoids

    Multiomics

  • Chromatin accessibility

  • 3' gene expression

    Singleplex throughput options

  • 10K nuclei/sample

  • 80K nuclei/chip

  • 8 samples/chip

Assay Components

Each experiment requires a chip, index kit, and core reagents. If you're unsure what you need, use the experiment builder to find the custom list of items required for your experiment.

Consumables

Choose a version


Nuclei Isolation (optional)

REAGENT

1001101

Nuclei Isolation Kit with RNase Inhibitor v2

Chip

CHIP

1000951

GEM-X Epi Multiome Chip Kit, 4 chips

Index Kit

REAGENT

1000212

Single Index Kit N Set A, 96 rxn

REAGENT

1000215

Dual Index Kit TT Set A 96 rxns

Core Reagents

REAGENT

1000979

GEM-X Epi Multiome, 16 samples

REAGENT

1000980

GEM-X Epi Multiome, 4 samples

RNase Inhibitor (optional)

REAGENT

1000887

Kit, RNase Inhibitor 40x

Compatible Instruments


Chromium XChromium iX

Build your own Epi Multiome experiment

Design the experiment that's right for you

Documents and resources

Videos

Cell Ranger ARC image

Cell Ranger ARC

Cell Ranger is a set of free analysis pipelines for processing Chromium Single Cell Multiome ATAC + Gene Expression data.

Loupe Browser image

Loupe Browser

Desktop application for Windows and MacOS that allows you to interactively visualize data.

Cloud Analysis image

Cloud Analysis

Cloud Analysis enables quick and easy access to Cell Ranger pipelines from your web browser.

Featured publications

Featured datasets

Epi ATAC

Chromatin accessibility profiling at the single cell level.

Universal 3'

Whole transcriptome gene expression profiling with broad species compatibility.

Universal 5'

5' gene expression alongside V(D)J repertoire profiling and antigen specificity of T and B cells.

Flex Apex

Probe-based whole transcriptome profiling for fresh, frozen, or fixed samples (even FFPE), plus 96-well multiplexing for highest throughput.

Chromium Single Cell

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