Loupe Browser

From data to biological insights

Loupe Browser is a powerful visualization software that provides intuitive analysis functionality you need to explore your 10x Genomics data. This easy-to-use desktop application for Windows and MacOS is available at no cost, enabling anyone to uncover biological insights from their data.

Loupe Browser
  • Multidimensional analysis

    Multidimensional analysis

    Interrogate different molecular readouts, within and across samples, to drive discovery.

  • Analysis with simple clicks

    Analysis with simple clicks

    Explore data with this user-friendly interface to deepen your biological understanding.

  • Expert support

    Expert support

    Leverage comprehensive software videos, tutorials, and more to accelerate your analysis.

  • Examine gene expression patterns

    Visualize expression profiles and differentially expressed genes across cell clusters.
  • Explore cell type compositions

    Examine and refine cell clusters to identify new or rare cell types.
  • Discover multiomic insights

    Utilize single cell gene and protein expression data to comprehensively profile new cell states.
  • Compare across samples

    Uncover differences in expression patterns, cell types, and their abundance.

Overlay gene expression and V(D)J data

  • Annotate immune cell subtypes by overlaying clonotype information onto gene expression profiles.
  • Visually explore links between phenotype and clonotype information by overlaying cell surface protein data.

Explore the immune repertoire

For our Single Cell Immune Profiling product, we provide an additional visualization software, Loupe V(D)J Browser, for more in-depth analysis of data.
  • Evaluate clonotype frequency, V(D)J gene usage, and pairing distribution to characterize T- and B-cell repertoire.
  • Visualize and compare key repertoire metrics across cell types and samples.
Single Cell Multiome ATAC + Gene Expression

Unify epigenomic and transcriptomic insights

  • Uncover multiomic markers for cell-type classification.
  • Refine cell types and states using simultaneous chromatin accessibility and gene expression measurements from the same single cells.
  • Investigate gene regulatory linkages between open chromatin peaks and gene expression.
Spatial Gene Expression

Visualize tissue transcriptomics

  • Analyze gene expression patterns to determine cell types and their localization within a tissue section.
  • Perform differential gene expression analysis across regions of interest.
  • Overlay gene expression, and protein expression onto tissue morphology.
Other Supported Analyses and Visualizations

Loupe Browser enables data analysis for many single cell applications

Epigenetics

Explore Single Cell ATAC data in Loupe Browser to perform differential chromatin accessibility analysis, find cell clusters enriched for transcription factor motifs of interest, and compare open chromatin profiles across samples.

Immune Receptor Mapping

Screen the binding specificities of multiple antigens or epitopes for B or T cells using Single Cell Immune Receptor Mapping. Obtain the corresponding paired, full-length receptor sequences for downstream expression and functional testing.

Multiomic Cytometry

Visualize and interpret results from your Multiomic Cytometry experiment for more robust cell-type identification using both cell surface proteins and gene expression readouts.

CRISPR Screening

Visualize data from Single Cell CRISPR Screening to characterize CRISPR perturbation phenotypes across guide targets and assess knockdown efficacy.

Frequently Asked Questions

Loupe V(D)J Browser is a separate visualization software application that provides specific functionality to analyze TCR and BCR clonotype information from the Single Cell Immune Profiling product.

Loupe Browser is a point-and-click software that enables anyone, no matter their level of bioinformatics expertise, to analyze 10x Genomics data.

Loupe Browser uses a .loupe file to visualize 10x Genomics data. The .loupe file is generated by running one of the compatible 10x Genomics Analysis Software applications, which processes raw data into standard file formats that can be used for downstream interpretation. Once you have the Analysis Software output, you can download the latest version of Loupe Browser and start to analyze your data.

The following resources are available to help you analyze data with Loupe Browser:

Loupe Browser is available at no cost to anyone analyzing 10x Genomics data.

Get Loupe Browser and explore documentation, tutorials and datasets for each product on our support site