The Chromium Single Cell Gene Expression Solution
Go Beyond Traditional Gene Expression Analysis
The Chromium Single Cell Gene Expression Solution provides a comprehensive, scalable solution for cell characterization and gene expression profiling of hundreds to tens of thousands of cells. Our latest improvements allow you to detect even more unique transcripts per cell and with the addition of Feature Barcoding technology, you can get a more complete molecular readout cell by cell—identify cell-specific CRISPR-mediated perturbations or simultaneously measure gene and cell surface protein expression in the same cell, with virtually unlimited possibilities for the additional feature types.
Go beyond traditional gene expression analysis to characterize cell populations, cell types, cell states, and more on a cell-by-cell basis. From assessing tumor heterogeneity and stem cell composition, to dissecting neuronal populations—the technological advancements provided by the Chromium Single Cell Gene Expression Solution, along with turnkey software tools, allow the creation of high complexity libraries from single cells to maximize insight from any sample type.
- Identify and characterize rare cell types
- Analyze and understand cellular heterogeneity and how this contributes to your biological system
- Perform cellular phenotyping with single cell RNA-seq to identify novel targets, biomarkers, and cell types and states without the need for pre-selected targets
- Evaluate mRNA and cell surface protein expression profiles within the same cell
- Perform high throughput and high resolution functional genetic screens in tens of thousands of cells simultaneously
- Assess comprehensive gene expression phenotypes for individual CRISPR perturbations
Gene Expression Profiling
Uncover cell-to-cell gene expression variability and identify rare cell types in heterogeneous samples to better characterize cellular contributions during development and disease. Our latest improvements vastly increase sensitivity, so you can detect even more unique transcripts per cell.Download Product Sheet
Feature Barcoding Technology: Cell Surface Protein
Better implement published methods like CITE-Seq/REAP-Seq with our new and improved workflow using Feature Barcoding technology. Seamlessly measure both gene and cell surface protein expression in the same cell to identify protein isoforms, detect protein for low abundance transcripts, and further increase phenotypic specificity.Download Product Sheet
Feature Barcoding Technology: CRISPR Screening
Identify CRISPR-mediated perturbations alongside cellular transcripts using Feature Barcoding technology. Implement this improved and novel methodology to conduct high-throughput and scalable functional genetic screens in hundreds to tens of thousands of single cells simultaneously.Download Product Sheet
Unlock Single Cell Analysis with These System Features
- Partition 500 – 80,000+ cells in under 9 minutes
- Superior sensitivity and cell capture rate up to 65%
- Simple workflow
- Cell size flexibility, no lower limits
- Low doublet rates of under 0.9% in 1,000 cells
Getting Started Guide:
Single Cell Gene Expression
Whether you have questions about how to design your experiments, optimize parameters, or identify the computational/analytical tools necessary to best analyze your single cell gene expression data, this guide has you covered. Take full advantage of the rich information enabled by single cell transcriptomic technology by downloading the getting started guide today!Download Getting Started Guide
Feature Barcoding Technology
Watch How it Works
See how combining our solution with Feature Barcoding technology allows you to dramatically increase the understanding of complex biological systems. Watch examples of how you can get a more complete cellular read-out, cell by cell—the possibilities are virtually limitless.
The Chromium Controller
Compact, Sleek, Efficient.
The compact, sleek Chromium Controller has been designed to rapidly and efficiently automate the equivalent of 100,000s to 1,000,000s of pipetting steps for highly parallel sample partitioning and molecular barcoding. The Chromium Controller allows a user to run any Chromium Solution, spanning from genome to single cell analysis. A dedicated Chromium Single Cell Controller is also available for users who exclusively run Single Cell Solutions.View Our Controller Gallery
To view a list of products by application type, first select your desired version of the Single Cell Gene Expression Solution. If you would like to combine this solution with Feature Barcoding technology, select Feature Barcode type(s).
Gene Expression Version
Feature Barcode Selection
Reagents & Consumables
Single Cell Gene Expression Datasets
Identifying Genetic Variation and Cellular Heterogeneity with a Comprehensive Cancer Analysis Toolkit
- AACRChicago, ILApril 15, 2018
- Keystone Symposia- Endoderm Development and DiseaseTaos, NMFebruary 26, 2018