Chromium Controller

The Controller is bowing out, take advantage of Chromium X benefits

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Chromium Controller instrument


Consider the X/iX advantage for your single cell research

  • We’re excited to offer you the opportunity to move your research forward like never before. The Chromium X Series instrument enables seamless scaling from pilot experiments through million-cell studies, and offers compatibility with an expanding range of Chromium Single Cell applications. This includes Single Cell Gene Expression Flex kits, which enable the most sensitive whole transcriptome profiling of fresh, frozen, and FFPE samples.

One system, many single cell approaches

  • The Chromium Controller uses advanced microfluidics to perform single cell partitioning and barcoding in a matter of minutes. Powered by Next GEM technology, the Chromium Controller enables integrated analysis of single cells at massive scale.
    Chromium instrument, left-facing angle, with measurements 8" x 8" x 12"
  • Our suite of Chromium Single Cell products can capture molecular readouts of cell activity in multiple dimensions, including gene expression, cell surface proteins, immune clonotype, antigen specificity, and chromatin accessibility. The key to this technology is its ability to generate tens of thousands of single cell partitions, each containing an identifying barcode for downstream analysis.
    Illustration of Next GEM technology showing the single cell barcoding process that takes place within the Chromium instrument
  • Resolve complex biology

    Uncover molecular insights and resolve highly complex biological systems. Capture the full heterogeneity of a sample, in tens of thousands of cells.

    Explore Biology Like Never Before: Chromium Single Cell Solutions

  • Multiomic cellular readout

    Gain more insights from precious samples. Measure mRNA, cell surface proteins, immune clonotype, antigen specificity, CRISPR perturbations, and chromatin accessibility. Uncover molecular insights, dissect cell-type differences, investigate the innate and adaptive immune system, detect novel subtypes and biomarkers, and map the epigenetic landscape, cell by cell.

    Single cell RNA sequencing can help connect datasets for multiple dimensions to reveal a rich picture of cell phenotypes

  • Flexible workflow

    Our suite of Chromium Single Cell products has been validated on fixed, fresh, and frozen samples, as well as whole cells and nuclei. Leverage biological insights with easy-to-use analysis and visualization software.

    Getting Started with Single Cell Gene Expression

Our End-to-End Solution

Chromium X Series

Chromium iX offers cost-effective, lower throughput single cell analysis, and can be easily upgraded to the high-throughput, full-range Chromium X.

Chromium Single Cell Reagents

With our reagent kits, capture and amplify mRNA, profile the immune repertoire, identify CRISPR perturbations, detect chromatin accessibility, and more.

Analysis and Visualization Software

Convert your data to biologically meaningful insights and interactively explore your results with easy-to-use software.

World-Class Technical and Customer Support

Our expert support team can be contacted by phone or email.

Frequently Asked Questions

At 10x Genomics, we are committed to enabling your research and providing you with the best experience to make scientific discoveries. As we release new technologies, we occasionally refine our on-market product offerings. 

The Chromium X Series instrument is our most flexible instrument, with the most advanced hardware and wireless connectivity. It runs all of our single cell assays, including new high-throughput assays for Single Cell Immune Profiling and Single Cell Gene Expression.

Please review our Product Obsolescence Notification for more details on product parts and Chromium Controller instrument support.

The Chromium Controller has a small instrument footprint that easily integrates into existing laboratory infrastructure.

  • Weight: 12.5 lb (5.6 kg)

  • Size: (W X D X H) 7.9 x 10.3 x 6.4 in (20 x 26.3 x 16.4 cm)

  • Ventilation Requirement: Minimum 4 in (10 cm) around all sides

  • Electrical Requirements: Nominal 100–240 Vac, 50–60 Hz, 25 W, from a standard 3-prong wall receptacle that includes a safety ground pin

  • Usable Temperature Range: 18–28°C (64–82°F)

  • Humidity: 85% Max (Non-Condensing)

  • Altitude: 0–6,560 ft (0–2,000 m)

For additional information, see the Chromium Controller Specifications manual

Chromium Controller Specifications manual

The Chromium Controller is compatible with our suite of Chromium Single Cell products, including Single Cell Gene Expression, Single Cell Immune Profiling, and Single Cell ATAC. Capture molecular readouts of cell activity in multiple dimensions, including gene expression, cell surface proteins, immune clonotype, antigen specificity, and chromatin accessibility.

Chromium Single Cell products require a number of assay-dependent reagents and consumables. Explore our Product Selector to determine the components necessary for your application. Additional kits, reagents, and laboratory equipment are required. Please see individual kit User Guides, available on our Support website for further details.

You can process between 1–8 samples in one run, loading up to 10,000 cells per sample.

Decontamination should be performed in accordance with institutional guidelines. For general guidance on how to clean the Chromium Controller, please review our Chromium Controller Specifications documentation

Chromium Controller Specifications documentation

Compatible Products