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Register nowEvery cell has a story. Tell them all with Chromium.
Single cell analysis enables meaningful discoveries
Bulk sequencing averages readouts, missing critical details driving complex biology. Single cell sequencing allows scientists to see the unique gene expression patterns of each cell. This view more fully characterizes tissue heterogeneity, revealing the rare cell types that have big consequences in health and disease.
The Chromium Advantage
Higher gene sensitivity and up to 80% cell recovery efficiency.
Enhanced detection of challenging cell types, including neutrophils.
Reduce hands-on time and lower the risk of errors with instrument-supported automation of the most critical workflow steps.
Produce higher quality libraries that can be sequenced at lower depths.
Backed by 10 years, over 2,200 patents, and >$1.5B in R&D investment.
Innovations developed for your success at every step
Access more sample types
Profile fresh, frozen, or fixed samples—even FFPE—with optimized protocols for proven performance
Automate critical steps to reduce error
Produce up to 8M barcoded partitions in just minutes, with up to 80% cell recovery
Construct high-quality sequence-ready libraries
Generate libraries with up to 95% usable reads, letting you detect more genes at lower sequencing costs
Analyze & discover with ease
Process and visualize your data with powerful software tools—no bioinformatics experience required
Performance, reproducibility & cost-efficiency built in
Broad, flexible portfolio of assays
Flex
Fix, batch, and run on your schedule.
Protein coding gene coverage: Performs well with low-quality and FFPE samples
Multiomic readouts from the same cell: Gene expression, Protein, CRISPR
Throughput options: Up to 8M cells (1–3,072 samples) per run
Universal
Species agnostic. Maximum versatility.
Whole transcriptome coverage: Delivers broadest set of information, including isoforms, SNPs, etc.
Multiomic readouts from the same cell: 3' or 5' gene expression, TCR/BCR, Protein, CRISPR
Throughput options: Up to 160,000 cells (1–8 samples) per run
Epi Chromatin
Unmask epigenomic profiles.
ATAC-seq chemistry: Explore open chromatin regions and link directly to 3' gene expression (Multiome kit)
Multiomic readouts from the same cell: Chromatin accessibility, 3' gene expression
Throughput options: Up to 80,000 nuclei (1–8 samples) per run
During the past years, we observed many advances in single cell technologies thanks to 10x Genomics. This multi-omics approach is very useful for scientists and for physicians to understand human disorders.David Michonneau, PhDProfessor of Hematology at Saint-Louis Hospital
Amplify your research gains
Gene expression
Characterize the unique transcriptomic profiles of each cell in your sample
CRISPR screening
Directly link CRISPR guide RNAs to the resulting perturbed phenotypes
Bring the Chromium advantage to your lab
A beginner’s guide to single cell RNA-seq
Introduction to GEM-X
Grant writing assistance
Buyer's Guide
Unlock the full spectrum of biology
| Platform | |||
| When to use | Comprehensive single cell dataIdeal for deep characterization of cell populations and states. | High-resolution spatial gene expressionUnderstand complex tissues, neighborhoods, and cell to cell interactions.
Integration with other spatial-omics, histology, and morphology. | |
| Why to use | Unbiased single cell discovery
High per-gene sensitivity | Unbiased spatial discovery | Targeted spatial exploration
High per-gene sensitivity |
| Applications | Whole transcriptome gene expression
Protein
TCR, BCR
CRISPR
ATAC | Whole transcriptome gene expression | Targeted gene expression (up to 5,000 genes) |
| Resolution | Single cell | Transcripts assigned to 2-µm areas | Single cell |
| Data readout | NGS-based | NGS-based | Imaging-based |
| Sample compatibility | Single cell or nuclei suspensions from fresh, frozen, or FFPE samples | FFPE
Fresh frozen
Fixed frozen | Fresh frozen
FFPE |
